Medicine Overview of Azole 400mg Tablet
Azole 400 is an antiparasitic medicine, used for the treatment of parasitic worm infections. It works by killing the worms that cause infections and stops the infection from spreading.
Azole 400 should be used in the dose and duration as advised by your doctor. Take it with or without food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.
Some people may experience vomiting, dizziness, increased liver enzymes, nausea and loss of appetite as the side effects of this medicine. Please consult your doctor if these side effects persist for a longer duration. You may be monitored with blood tests and liver function tests throughout your treatment.
- Parasitic worm infections
- Vomiting
- Dizziness
- Increased liver enzymes
- Nausea
- Loss of appetite
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You have been prescribed Azole 400 to treat a variety of parasitic worm infections.
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It can be harmful to an unborn baby. Do not take it during pregnancy or breastfeeding. Use birth control measures to prevent pregnancy while taking Azole 400.
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Your doctor may monitor your blood counts and liver function before you start taking this medicine and regularly throughout your treatment.
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Avoid being near people who are sick or have infections. Inform your doctor if you develop signs of infection.
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Do not skip doses and finish the prescribed course, even if you start to feel better. Stopping it early may increase your risk of further infection.
Echinococcosis
Adult: <60 kg: 15 mg/kg daily in 2 divided doses. Max: 800 mg/day. ?60 kg: 400 mg bid. Admin dose for three 28-day cycles w/ a 14-day drug-free interval in between each cycle.
Neurocysticercosis
Adult: <60 kg: 15 mg/kg daily in 2 divided doses (max: 800 mg/day) for 8-30 days. ?60 kg: 400 mg bid for 8-30 days.
Ancylostoma, Ascariasis, Hookworm, Trichostrongylus
400 mg PO once
Monitor blood counts and liver function. Administer within 7 days of start of normal menstruation in women of childbearing age. Adequate nonhormonal contraceptive measures must be taken during and for 1 mth after therapy. Perform liver function tests and blood counts before and every 2 wk during high dose therapy of hydatid disease.
Lactation: unknown, use caution.
>10%
Headache,Neurocysticercosis (11%),Hydatid disease (1.3%),Abnormal LFT,Hydatid disease (15.6%),Neurocysticercosis (<1%)
1-10%
Abdominal pain,Hydatid disease (6%),Nausea/vomiting,Hydatid disease (3.7%),Neurocysticercosis (6.2%),Dizziness/vertigo,Hydatid disease (1.2%),Neurocysticercosis (<1%),Increased intracranial pressure,Neurocysticercosis (1%),Meningeal signs,Neurocysticercosis (1%),Alopecia (reversible),Hydatid disease (1.6%),Neurocysticercosis (<1%),Fever,Hydatid disease (1%)
<1% (selected)
Rash,Urticaria,Agranulocytosis,Aplastic anemia,Bone marrow suppression,Granulocytopenia,Pancytopenia,Thrombocytopenia,Hepatitis,Acute liver failure,Acute renal failure
Potentially Fatal: Bone marrow depression.
