Medicine Overview of Derfin 250mg Tablet
Derfin is used to treat a wide range of fungal infections of the skin and nails, including ringworm. It works by killing the fungus that causes the infection.
Derfin is for external use only. It should be used in the dose and duration suggested by the doctor. Applying it at the same time every day will help you remember to use it. The affected area should be clean and dry before application of the ointment. You must wash your hands thoroughly before and after applying this medicine. Do not stop using it until you have finished the complete course, even when you feel better. If you stop using this medicine too early, the fungus may continue to grow and the infection may return or worsen.
The most common side effects of this medicine include application site reactions like burning, irritation, itching, and redness. These are usually mild but let your doctor know if they bother you or last more than a few days. Avoid direct contact with eyes, nose, or mouth. If accidental exposure occurs, rinse immediately with plenty of water. You must inform your doctor if there’s no improvement even after four weeks of treatment.
It is not likely that other medicines you take by mouth or injection will affect the way it works but talk to your doctor before using it if you have used a similar medicine before and had an allergic reaction. Pregnant and breastfeeding mothers should consult their doctor before using it.
- Fungal skin infections
- Skin peeling
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Derfin helps treat skin infections caused by many different types of fungi.
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Finish the full course of treatment even if you feel better.
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It can take a few weeks for the infection to clear and a few months before the skin returns to its normal color.
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Apply an amount sufficient to cover the affected area and 1 inch of the immediate surrounding skin.
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It can make your skin more sensitive to sun. Use broad-spectrum sunscreen and protective clothing when outdoors.
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Avoid getting in the eyes, nose, or mouth. If accidental exposure occurs, rinse immediately with plenty of water.
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Inform your doctor if the infection has not cleared up after four weeks of treatment.
Oral
Onychomycosis
Adult: 250 mg once daily for 6 weeks (fingernail) or 12 weeks (toenail)
Tinea Pedis, Tinea Corporis, Tinea Cruris
Adult: 250 mg/day PO in single dose or divided q12hr
2-4 wk in tinea cruris, tinea corporis
2-6 wk for tinea pedis
Hepatic impairment: Use not recommended in chronic or active liver disease
Tinea Capitis
>4 years (<25 kg): 125 mg/day PO for 6 weeks
>4 years (25-35 kg): 187.5 mg/day PO for 6 weeks
>4 years (>35 kg): 250 mg/day PO for 6 weeks
Renal impairment: Use not recommended if CrCl <50 mL/min
Preexisting liver or renal impairment, pregnancy. Perform liver function tests prior to oral therapy.
Lactation: Drug excreted in breast milk; do not use
>10%
Headache (13%)
1-10%
Rash (6%),Pruritus (3%),Nausea (3%),Diarrhea (6%),Dyspepsia (4%),Abdominal pain (2%),Taste disturbance (3%),Elevated liver function test results (3%),Visual disturbance (1%)
Potentially Fatal: Liver failure, Stevens-Johnson syndrome, neutropaenia.
