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Zofen TS

Name: Zofen TS
SKU: SKU-PZJbntn7
Availability: InStock

Tablet - 1.5mg

Aristopharma Limited

Generic: Pizotifen

10 Tablets (1 Strip)

Original price was: Tk. 72.Current price is: Tk. 64.

Description

Medicine Overview of Zofen TS 1.5mg Tablet

Introduction

Zofen TS is a medicine used for the prevention of migraine. However, it cannot treat an acute attack and will only work to prevent migraines for as long as you continue to take the medicine. This medicine relaxes the brain, preventing migraine headache.

Zofen TS may be taken with or without food, preferably at night. However, it is advisable to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Do not skip any doses and finish the full course of treatment even if you feel better. If you have missed a dose, take it as soon as you remember it.

Side effects associated with the use of this medicine include dryness in mouth, increased appetite, and feeling sick. It may cause sleepiness in the beginning of your treatment, do not drive or operate machinery until you know how this medicine affects you. It may also cause weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly to prevent it.

It is important to consult your doctor if you develop a skin rash, muscle aches, tremors, or difficulty moving after taking this medicine. You should avoid alcohol consumption while taking this medicine as it may result in increased sedation. If you are taking this medicine for a long-term, regular monitoring of liver function and vision is recommended.

Uses of Zofen TS

Migraine

Side effects of Zofen TS

Common

Sleepiness
Dryness in mouth
Increased appetite
Dizziness
Drowsiness
Feeling sick

How to use Zofen TS

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zofen TS may be taken with or without food, but it is better to take it at a fixed time.

How Zofen TS works

Migraine headaches are thought to result from the dilatation of blood vessels in the head. Zofen TS is a serotonin antagonist. It works by maintaining the level of serotonin (chemical messenger) in the brain and also prevents loss of tone and dilation of blood vessels, thus preventing the migraine headache.

What if you forget to take Zofen TS?

If you miss a dose of Zofen TS, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

You have been prescribed Zofen TS for the prevention of migraine headaches.

Do not take it to treat an acute attack of migraine.

Some tips that may help avoid a migraine attack:

It should be taken at night-time before going to bed.

It may cause sleepiness. Don’t drive or do anything that requires mental focus until you know how Zofen TS affects you.

You may experience weight gain while on treatment. Monitoring of body weight is required on a regular basis.

Notify your doctor if you develop skin rash, muscle aches, tremors, difficulty moving, or abnormal uncontrolled movement.

Brief Description

Indication

Headache, Migraine

Administration

May be taken with or without food.

Adult Dose

Oral
Prophylaxis of migraine; Prophylaxis of cluster headache
Adult: Initially, 0.5 mg, increase gradually as necessary.
Maintenance: 1.5 mg daily as a single dose at night or in 3 divided doses.
Max: 4.5 mg daily (max ?3 mg/dose).

Hepatic impairment: Dose adjustment may be needed.

Child Dose

Oral
Prophylaxis of migraine; Prophylaxis of cluster headache
Child: >2 yr Initially, 0.5 mg. May increase gradually up to 1.5 mg daily in divided doses (max 1 mg/dose).

Renal Dose

Renal impairment: Dose adjustment may be needed.

Contraindication

Premature infants or neonates. Postural giddiness.

Mode of Action

Pizotifen is a sedating antihistamine with strong serotonin antagonist and weak antimuscarinic properties. It also antagonises the action of tryptamine.

Precaution

Patient w/ angle-closure glaucoma, urinary retention, epilepsy. Avoid abrupt withdrawal. Renal and hepatic impairment. Childn. Pregnancy and lactation. Patient Counselling This drug may cause drowsiness, somnolence and dizziness, if affected, do not drive or operate machinery. Monitoring Parameters Monitor hepatic function (prolonged use), wt gain, BP.

Side Effect

Increased appetite, nausea, wt gain, drowsiness, dizziness, dry mouth, fatigue, muscle pain or cramps, heavy or restless legs, fluid retention, facial flushing, reduced libido, exacerbation of epilepsy, dreaming, hepatic injury.

Interaction

Enhances sedative effects of CNS depressants. Additive antimuscarinic action with other antimuscarinic drugs. May mask warning signs of damage caused by ototoxic drugs eg, aminoglycosides.