Medicine Overview of Besiflox 0.60% Eye Drop
Besiflox is an antibiotic, used in the treatment of bacterial infections of the eye. It relieves the symptoms of the infection by stopping the further growth of the causative microorganisms.
Besiflox is for external use only. Take it in the dose and duration as advised by your doctor. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid. Avoid skipping any doses and finish the full course of treatment even if you feel better.
It may cause burning sensation and eye discomfort immediately following application. However, these side effects are temporary and usually subside on their own. Inform your doctor if they persist for a longer duration. It may cause short term blurring of vision when first used. Use caution before driving or using machines. Do not wear contact lenses while using it.
- Bacterial eye infections
- Burning eyes
- Eye discomfort
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You have been prescribed Besiflox for the treatment of bacterial infections of the eye.
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Do not skip any doses and finish the full course of treatment even if you feel better.
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Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the medication.
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Do not touch the tip to any surface, or to your eye, to avoid contamination.
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Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
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It may cause short term blurring of vision when first used. Use caution before driving or using machines.
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Do not wear contact lenses until your infection clears up.
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Make sure to use within 4 weeks of opening the medication.
Bactericidal
Inhibits DNA-gyrase (a topoisomerase) in susceptible organisms, which in turn inhibits cell division.
• This drug is for topical ophthalmic use only and should not be injected subconjunctivally, nor should it be introduced directly into the anterior chamber of the eye.
• As with other anti-infectives, prolonged use may result in overgrowth of non-susceptible organisms, including fungi. If superinfection occurs, discontinue use and institute alternative therapy.
• To prevent contamination do not touch the tip of the dropper to eye, eyelid or any surface of the affected eye.
• Patients should not wear contact lenses during the course of therapy with this drug.
• Shake well before use.
Lactation: Excretion in milk unknown; use caution
1-10%
Blurred vision,Conjunctival redness,Eye irritation,Eye pain,Eye pruritus,Headache
Pregnancy
There are no available human data during pregnancy to inform any drug-associated risks; however, systemic exposure to besifloxacin from ocular administration is low; oral administration of besifloxacin to pregnant rats during organogenesis or during pre/postnatal period did not produce adverse embryofetal or offspring effects at clinically relevant systemic exposures
Lactation
There are no data on presence of drug in human milk, effects on breastfed infant, or on milk production; however, systemic exposure to besifloxacin following topical ocular administration is low, and it is not known whether measurable levels of besifloxacin would be present in maternal milk following topical ocular administration
The developmental and health benefits of breastfeeding should be considered, along with mother’s clinical need for therapy, and any potential adverse effects on breastfed infant from treatment
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