A-Clox 500

Introduction
A-Clox 500 is an antibiotic used to treat various bacterial infections. It is effective in infections of the throat, ear, nasal sinuses, respiratory tract, and skin and soft tissue. It mainly fights and stops the growth of the gram-positive type of bacteria. A-Clox 500 should be taken on an empty stomach. For best results, it should be used regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication. Before taking this medicine, inform your doctor if you are allergic to penicillin or penicillin-type of medicine. Nausea, vomiting, and diarrhea may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision.

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Uses of A-Clox 500
Bacterial infections
Side effects of A-Clox 500
Common
Rash
Vomiting
Allergic reaction
Nausea
Diarrhea
How to use A-Clox 500
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. A-Clox 500 is to be taken empty stomach.
How A-Clox 500 works
A-Clox 500 is an antibiotic. It kills bacteria by preventing them from forming their own protective covering (cell wall) which is needed for them to survive.
Quick Tips
You have been prescribed Myoclox CV 625mg Tablet for the treatment of bacterial infections.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Take it with food and plenty of fluids to avoid an upset stomach.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn’t stop or if you find blood in your stools.
Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.
Brief Description
Indication
Staphylococcal infections resistant to benzylpenicillin
Administration
Should be taken on an empty stomach. Take on an empty stomach 1 hr before or 2 hr after meals. Reconstitution: IM: The contents of each vial should be dissolved in 1.5 mL of water for inj. IV: 500 mg to be dissolved in 10-20 mL of water for inj, added to suitable IV fluids if given for i

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Adult Dose
Oral Adult: 250-500 mg 4 times/day. Parenteral Adult: 1-2 g 6 hrly. For more severe infections (e.g. meningitis, endocarditis), 2 g 4 hrly.

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Child Dose
Oral Child: 50-100 mg/kg in divided doses every 6 hr.

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Contraindication
Hypersensitivity to cloxacillin and other penicillins.
Mode of Action
Cloxacillin inhibits bacterial cell wall synthesis by binding to 1 or more of the penicillin-binding proteins (PBPs) which in turn inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. Bacteria eventually lyse due to ongoing activity of cell wall autolytic enzymes (autolysins and murein hydrolases) while cell wall assembly is arrested.
Precaution
Patient w/ allergies esp β-lactam allergy, asthma, history of seizure disorder. Renal impairment. Pregnancy and lactation. Monitoring Parameters Observe for signs and symptoms of anaphylaxis during 1st dose. Monitor CBC w/ differential (prior to initiating therapy and wkly thereafter), periodic BUN, creatinine, hepatic function.
Side Effect
Hypotension, confusion, fever, lethargy, seizure, pruritus, rash, urticaria, abdominal pain, black or hairy tongue, diarrhoea, flatulence, nausea, oral candidiasis, pseudomembranous colitis, stomatitis, vomiting, agranulocytosis, bone marrow depression, eosinophilia, granulocytopenia, haemolytic anaemia, leucopenia, neutropenia, thrombocytopenia, increased alkaline phosphatase, ALT and AST, hepatotoxicity, thrombophlebitis, arthralgia, myalgia, myoclonus, hematuria, interstitial nephritis, proteinuria, renal insufficiency, renal tubular damage, bronchospasm, laryngeal oedema, laryngospasm, sneezing, wheezing, angioedema, allergic reaction, serum sickness-like reaction. Potentially Fatal: Anaphylaxis.

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Interaction
May diminish the effect of BCG and typhoid vaccine. May increase risk of methotrexate toxicity. May diminish the therapeutic effect of Na picosulfate. May decrease serum concentrations of mycophenolate. May prolong bleeding time w/ anticoagulants. Increased serum concentrations w/ probenecid. Tetracycline may antagonise the bactericidal effect of cloxacillin.
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A-Clox 500
Capsule
– (500mg)
arogga-brand
The ACME Laboratories Ltd.
Generic: Cloxacillin
4 Capsules (1 Strip)
৳ 21.75
৳ 23.92
9% OFF
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