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Abaclor PD

Paediatric Drops
Generic: Cefaclor
1 x 15ml bot

Original price was: Tk. 135.Current price is: Tk. 122.

Description

 

Medicine Overview of Abaclor PD Paediatric Drops

Introduction

Abaclor PD is an antibiotic medicine used to treat bacterial infections in your body. It is effective in infections of the lungs (e.g. pneumonia), ear, throat, nasal sinus, urinary tract, skin, soft tissues, bones, and joints. It is also used to prevent infections during surgery.

Abaclor PD may be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. The dose will depend on what you are being treated for, but you should always complete a full course of this antibiotic as prescribed by your doctor. Do not stop taking it until you have finished, even when you feel better. If you stop taking it early, some bacteria may survive and the infection may come back. It will not work for viral infections such as flu or the common cold. Using any antibiotic when you do not need it can make it less effective for future infections.

The most common side effects of this medicine include rash, vomiting, nausea, diarrhea, and changes in liver function tests. These are usually mild but let your doctor know if they bother you or last more than a few days.

Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. You should also let your doctor know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it. Avoid consuming alcohol while taking this medicine as it may cause unpleasant side effects like nausea, vomiting, sweating, anxiety, and palpitations.

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Uses of Abaclor PD
  • Bacterial infections
Side effects of Abaclor PD
Common
  • Rash
  • Vomiting
  • Allergic reaction
  • Nausea
  • Injection site reaction
  • Increased liver enzymes
  • Diarrhea
How to use Abaclor PD
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Abaclor PD may be taken with or without food, but it is better to take it at a fixed time.
How Abaclor PD works
Abaclor PD is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.
What if you forget to take Abaclor PD?
If you miss a dose of Abaclor PD, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
  • Your doctor has prescribed Uniclor 375mg Tablet MR to cure your infection and improve your symptoms.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
  • Discontinue Uniclor 375mg Tablet MR and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
  • Take it with food to avoid an upset stomach.
  • Avoid consuming alcohol while taking Uniclor 375mg Tablet MR as it may cause increased side effects.
Brief Description
Indication
Pneumonia, Meningitis, Peritonitis, Otitis media, Septicaemia, Biliary-tract infections, Urinary-tract infections, Skin and skin structure infections, Upper and lower respiratory tract infections, Pharyngitis, Tonsillitis
Administration
May be taken with or without food.
Adult Dose

Oral
Urinary tract infections, Upper and lower respiratory tract infections, Skin infections, Otitis media
Adult: As monohydrate: 250-500 mg every 8 hr. Max: 4 g daily.

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Child Dose

Oral
Urinary tract infections, Upper and lower respiratory tract infections, Skin infections, Otitis media
Child: PO 20–40 mg/kg/day, max 1 g/day q12h

1-5 yr: 125 mg tid,
>5 yr: 250 mg tid.

Suspension & Paediatric Drops:
1 month – 1 year 2.5 ml t.i.d. 0.625 ml t.i.d
1 year – 5 year 5 ml t.i.d. 1.25 ml t.i.d
over 5 years 10 ml t.i.d 2.5 ml t.i.d

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Renal Dose

Renal Impairment
CrCl: 10-50 mL/min: Half to full dose

CrCl: <10 mL/min: Half dose

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Contraindication
Known hypersensitivity to cephalosporins.
Mode of Action
Cefaclor binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death. It has bactericidal activity against gm-ve bacteria including E. coli, S. pneumoniae, N. gonorrhoea, P. mirabilis and H. influenzae.
Precaution

Severe renal impairment; history of allergy to penicillin; pregnancy, lactation.

Lactation: enters breast milk; use with caution

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Side Effect

1-10%
Diarrhea (3%),Increased transaminases (3%),Eosinophilia (2%),Moniliasis (2%),Vaginitis (2%),Rash (maculopapular, erythematous, or morbiliform) (1-2%)

<1%
Stevens-Johnson syndrome,Pseudomembranous colitis,Nausea,Vomiting,Anemia,Neutropenia,Jaundice

Potentially Fatal: Anaphylactic reaction; pseudomembranous colitis.

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Pregnancy Category Note

Pregnancy
No adequate and well-controlled studies in pregnant women

Because animal reproduction studies are not always predictive of human response, cefaclor should be used during pregnancy only if necessary

Lactation
Effect on nursing infants is unknown; exercise caution when cefaclor is administered to a nursing woman

Extended-release tablets
No studies in lactating women performed; small amounts of cefaclor (?0.21 mcg/mL) detected in human milk following administration (single 500-mg dose of cefaclor extended-release tablets)

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Interaction
May enhance the nephrotoxic effect of aminoglycosides. May diminish the therapeutic effect of BCG, typhoid vaccine and Na picosulfate. Concomitant use w/ warfarin may increase prothrombin time. Probenecid inhibits renal excretion of cefaclor.
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