Medicine Overview of Antial 12mg Tablet
Antial 12 is used to treat mild to moderate dementia in Alzheimer’s disease, a progressive illness which gradually affects memory and thinking. It does not cure this illnesses but may help improve memory, awareness and other symptoms.
Your doctor will explain how to take Antial 12 and give you the one most suitable for you. Follow the instructions carefully to get the most benefit. The dose may change from time to time to suit your individual needs. You may take it with food, preferably at night before going to bed. It can take up to few weeks for symptoms to improve so keep taking your medicine regularly. You should not stop taking this medicine without consulting your doctor.
Some common side effects of this medicine include diarrhea, nausea, vomiting, loss of appetite and weight loss. Some people may experience dizziness, increase in blood pressure or decreased heart rate. You may have side effects more often when you start your treatment or when your dose is increased. Usually, the side effects will slowly go away as your body gets used to the Antial 12. If they are severe or will not go away, you should contact your doctor.
Before using Antial 12, you should tell your doctor if you have ever had heart problems, stomach ulcer, epilepsy or asthma. It may also affect, or be affected by, some other drugs you are using so let your doctor know what these are to be safe. During pregnancy this medicine should only be taken if it is advised.
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- Alzheimer's disease
- Nausea
- Vomiting
- Diarrhea
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You have been prescribed Antial 12 to slow down the progression of Alzheimer’s disease.
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It does not cure Alzheimer’s disease but may help improve brain function and ability to do daily activities.
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Take it with or without food, preferably at night before going to bed.
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It may cause diarrhea, nausea, and vomiting. Drink plenty of fluids to keep yourself hydrated while taking Antial 12.
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Monitor your body weight regularly as both Antial 12 and Alzheimer’s disease can cause weight loss.
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Do not drive or do anything that requires mental focus until you know how Antial 12 affects you.
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It may cause serious skin rashes. Stop taking medication and inform your doctor if you notice a skin rash.
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Inform your doctor if you develop muscle tremors, especially if you have Parkinson’s disease.
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Inform your doctor about taking Antial 12, If you are going to have surgery under anesthesia.
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Be cautious while taking this medicine if you suffer from peptic ulcer as it may cause vomiting, stomach bleeding, stomach pain, or discomfort.
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Inform your doctor if you experience seizures or convulsions while taking this medicine.
Alzheimer Disease
Initial
4 mg PO q12hr
Maintenance
Titrate to 8-12 mg PO q12hr; increase by 4 mg q12hr at no less than 4 week intervals
Hepatic Impairment
Moderate: (Child-Pugh score 7-9): Not to exceed 16 mg/day
Severe: Not recommended
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Not recommended
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Renal Impairment
Moderate: Not to exceed 16 mg/day
Severe (CrCl <9 mL/min): Not recommended
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>10%
Nausea (20-25%),Diarrhea (11-15%),Vomiting (11-15%)
1-10%
Abdominal pain,Anorexia,Muscle cramp,Fatigue,Dizziness,Headache,Weight loss,Depression,Insomnia,UTI,Somnolence,Anemia,Syncope,Bradycardia
Potentially Fatal: CV effects; convulsion; delirium; rectal haemorrhage; thrombocytopenia.
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ncreased serum concentrations when used with drugs that inhibit CYP2D6 (e.g. quinidine, fluoxetine, fluvoxamine, and paroxetine) and CYP3A4 (e.g. ketoconazole and ritonavir). Cimetidine may increase the bioavailability of galantamine. Increased risk of gastric ulcer when used with NSAIDs.
Potentially Fatal: Amiodarone, ?-blockers, diltiazem or verapamil; NSAIDs; digoxin.
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