Medicine Overview of Aristomol 0.25% 0.25% Eye Drop
Aristomol 0.25% is a beta-blocker used to treat elevated intraocular pressure (high pressure inside the eye) in people with ocular hypertension or open angle glaucoma. It lowers the pressure in the eye by decreasing the production of fluid and reduces the risk of vision loss.
Always wash your hands before using Aristomol 0.25%. Use only the number of drops that your doctor has prescribed and wait for about 5 minutes between each drop. If you wear soft contact lenses, remove them before using the drops and wait for at least 15 minutes before putting them back in. If you are also using another eye medicine, wait for at least 10 minutes before using it. Read the leaflet that comes with the medicine for a full guide on how to use the drops and get the most benefit. Do not touch the tip of the dropper or bottle. This may lead to infection. You should use this medicine regularly to get the most benefit and it is best used at the same time(s) each day. If you want to stop using it, consult your doctor first.
The most common side effects are burning and stinging sensation in the eye. There are other, less common, side effects affecting other parts of the body some of which may be serious as Aristomol 0.25% is absorbed into the systemic circulation. Consult your doctor if you are bothered by any side effects.
You should not use this medicine if you have asthma, severe COPD (chronic obstructive pulmonary disease) or a serious heart condition. Inform your doctor if you have, or have had, coronary heart disease, heart failure, diabetes, breathing problems, an overactive thyroid gland or liver or kidney disease. Pregnant or breastfeeding women should consult their doctor before taking this medicine.
- Glaucoma
- Ocular hypertension
- Burning eyes
- Stinging in the eyes
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Aristomol 0.25% helps lower high pressure in the eye and reduces the risk of vision loss.
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Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop.
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Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
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Notify your doctor if you have lung or heart diseases as Aristomol 0.25% may worsen these conditions.
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Stinging sensation may occur for 1-2 mins. Notify your doctor if it persists for longer.
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Make sure to use within 4 weeks of opening the bottle.
Ophthalmic
Open-angle glaucoma; Ocular hypertension
Adult: As eye drop soln: Initial: Instill 1 drop of 0.25% soln to affected eye(s) twice daily, increase to 1 drop of 0.5% soln twice daily if needed. Reduce to 1 drop/day if controlled.
Safety & efficacy not established
Observe patients receiving topical timolol and a systemic ß-adrenergic blocking agent concomitantly for potential additive effects on IOP and/or systemic effects of ß-adrenergic blockade
Severe respiratory reactions and cardiac reactions, including death due to bronchospasm in patients with asthma, and rarely death in association with cardiac failure, reported following systemic or ophthalmic administration of timolol maleate
Patients with chronic obstructive pulmonary disease (e.g., chronic bronchitis, emphysema) of mild or moderate severity, bronchospastic disease, or a history of bronchospastic disease (other than bronchial asthma or a history of bronchial asthma, in which timolol is contraindicated) should, in general, not receive beta-blockers
Some authorities recommend gradual withdrawal of beta-adrenergic receptor blocking agents in patients undergoing elective surgery; if necessary during surgery, effects of beta-adrenergic blocking agents may be reversed by sufficient doses of adrenergic agonists
Beta-adrenergic blocking agents should be administered with caution in patients subject to spontaneous hypoglycemia or diabetic patients (especially those with labile diabetes) who are receiving insulin or oral hypoglycemic agents; beta-adrenergic receptor blocking agents may mask signs and symptoms of acute hypoglycemia
Beta-adrenergic blocking agents may mask certain clinical signs (e.g., tachycardia) of hyperthyroidism; patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-adrenergic blocking agents that might precipitate thyroid storm
Because of potential effects of beta-adrenergic blocking agents on blood pressure and pulse, these agents should be used with caution in patients with cerebrovascular insufficiency; if signs or symptoms suggesting reduced cerebral blood flow develop following initiation of therapy, alternative therapy should be considered
>10%
Burning or stinging (38%)
>1%
Blurred vision (4-10%),Cataract (4-10%),Conjunctivitis (4-10%),Decreased visual acuity (4-10%),Headache (4-10%),Hypertension (4-10%),Infection (4-10%),Itching (4-10%)
Frequency Not Defined
Ocular irritation,Blepharitis,Keratitis,Ocular pain,Discharge (e.g., crusting),Foreign body sensation,Dry eyes,Eyelid erythema,Blepharoptosis,Decreased corneal sensitivity,Diplopia,Cystoid macular edema,Pseudopemphigoid,Choroidal detachment following filtration surgery,Epiphora,Photophobia,Conjunctival injection,Corneal fluorescein staining,Retinal vascular disorder,Ptosis
Potentially Fatal: Heart failure, intensification of heart block, bronchospasm, respiratory failure.

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