Introduction
Busper is a prescription medicine used for the treatment of anxiety disorder. It alters the chemicals in the brain that cause symptoms of anxiety such as irritability, restlessness, lack of concentration, fatigue, sweating, increased heart rate and unwanted or racing thoughts. Busper may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms. Some common side effects of this medicine include nausea, headache, vomiting, and dry mouth. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you and do not take alcohol with it as it may worsen the dizziness. Before taking this medicine, remember to inform your doctor if you have any medical conditions like acute narrow-angle glaucoma, myasthenia gravis, slurred speech, or drug dependence issues.
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Uses of Busper
Anxiety disorder
Side effects of Busper
Common
Nausea
Headache
Vomiting
Dryness in mouth
Sleepiness
Dizziness
Constipation
Diarrhea
Abdominal pain
How to use Busper
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Busper may be taken with or without food, but it is better to take it at a fixed time.
How Busper works
Busper works by modulating the action of serotonin, a chemical messenger of the brain that affects thoughts and mood.
What if you forget to take Busper?
If you miss a dose of Busper, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Take it at the same time every day to help you remember to take it.
It may take 2-4 weeks to achieve efficacy.
Use caution while driving or doing anything that requires concentration as Busper can cause dizziness and sleepiness.
Avoid consuming alcohol while taking this medicine as it may cause excessive drowsiness.
Do not stop taking medicine without talking to your doctor first.
Brief Description
Indication
Anxiety
Administration
May be taken with or without food. Take consistently either always w/ or always w/o meals.
Adult Dose
Anxiety Disorders 10-15 mg/day PO divided q8-12hr; may increase every 2-3 days by 5 mg/day to 15-30 mg/day PO divided q8-12hr; not to exceed 60 mg/day Hepatic impairment: Not recommended for patients with severe impairment
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Renal Dose
Renal impairment: Not recommended for patients with severe impairment
Contraindication
Hypersensitivity. Epilepsy; severe renal or hepatic impairment; children <18 yr; pregnancy, lactation.
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Mode of Action
Buspirone exerts anxiolytic activity through high affinity for serotonin 5-HT1A and 5-HT2 receptors. It has moderate affinity for dopamine D2-receptors but no affinity for GABA receptors.
Precaution
Preceding co-administration of MAOIs, decreased hepatic or renal function. In patients on benzodiazepines, withdraw the drug gradually. May impair ability to drive or operate machinery. Lactation: Excretion in milk unknown/not recommended
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Side Effect
>10% Dizziness (12%) 1-10% Drowsiness (10%),Nausea (8%),Headache (6%),Nervousness (5%),Blurred vision (2%),Confusion (2%),Diarrhea (2%),Excitement (2%),Insomnia (2%),Myalgia (1%),Numbness (2%),Paresthesia (1%),Rash (1%),Tremor (1%),Weakness (2%),Nasal congestion (1%),Sore throat (1%),Nonspecific chest pain (1%),Tinnitus (1%),Dream disturbances (1%) <1% Akathisia,Allergic reaction,Anorexia,Bruising,Galactorrhea,Heart failure,Menstrual irregularity,Suicidal ideation,Syncope,Alopecia,Eosinophilia,Edema,Enuresis,Increased ocular pressure,Visual disturbances,Rectal bleeding,Photophobia,Dystonia
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Pregnancy Category Note
Pregnancy category: B Lactation: Excretion in milk unknown/not recommended
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Interaction
Enhanced sedative effects with alcohol or CNS depressants. Increases serum haloperidol. Concurrent admin with MAOIs may lead to increase in BP. Potentially Fatal: Elevation of BP when taken concomitantly with MAOIs.
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