Calson

Indication
Heartburn, Calcium supplement, Calcium deficiencies
Administration
Should be taken with food.
Adult Dose
Adult: PO 19-50 yr: 1,000 mg elemental Ca/day and >50 yr: 1,200 mg elemental Ca/day.

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Renal Dose
Renal impairment (frequent monitoring of serum calcium and phosphorus is recommended);
Contraindication
Conditions associated with hypercalcaemia and hypercalciuria.
Mode of Action
Calcium is used to prevent or treat negative calcium balance. It also helps facilitate nerve and muscle performance as well as normal cardiac function. Bone mineral component; cofoactor in enzymatic reactions, essential for neurotransmission, muscle contraction, and many signal transduction pathways.
Precaution
Sarcoidosis; history of nephrolithiasis. Avoid IV admin of calcium in patients on cardiac glycosides. Increased risk of hypercalcaemia and hypercalciuria in hypoparathyroid patients receiving high doses of vitamin D. Caution when used in patients with history of kidney stones. Patients should be advised to administer vitamin D concurrently to optimise calcium absorption. Pregnancy.
Side Effect
GI discomfort e.g. nausea, vomiting, constipation; bradycardia, arrhythmias. Dry mouth, increased thirst or increased urination. Mental confusion, milk-alkali syndrome.
Interaction
May reduce the efficacy of calcium-channel blockers. Concurrent admin of IV calcium salt with cardiac glycosides may lead to serious adverse events. Increased risk of hypercalcaemia when used with thiazide diuretics. May reduce absorption of tetracycline, alendronate, atenolol, iron, quinolone antibiotics, sodium fluoride and zinc.