Cantina

Indication
Skin and nail fungal infections, Tinea pedis, Tinea cruris, Tinea corporis, Candidiasis, Pityriasis versicolor
Adult Dose
Topical/Cutaneous Skin and nail fungal infections: Adult: Apply 2 or 3 times daily. Onychomycosis: for 6 months. Tinea pedis & Dermatomycoses: for 4 weeks.

_
Child Dose
Tinea Corporis/Tinea Pedis Apply to affected area q12hr for 4 weeks Tinea Cruris >2 years: Apply to affected area q12hr for 2 weeks Candidiasis Gently massage sufficient clotrimazole into affected and surrounding area q12hr; reconsider diagnosis if no improvement after 4 weeks Tinea Versicolor Gently massage sufficient clotrimazole into affected and surrounding area q12hr; reconsider diagnosis if no improvement after 4 weeks

_
Contraindication
Hypersensitivity.
Mode of Action
Clotrimazole is a broad-spectrum antifungal which binds to phospholipids in the cell membrane altering cell wall permeability causing a loss in essential intracellular elements.
Precaution
Avoid contact with eyes upon topical application. Childn <3 yrs. Pregnancy, lactation.If local intolerance develops, consider withdrawal of the medicine and institution of appropriate therapy. Lactation: Excretion in milk unknown; use with caution _ Side Effect Elevated serum AST (SGOT) concentrations (15%) Topical: Erythema, stinging, irritation; hypersensitivity reactions; contact dermatitis. Edema, Pruritus, Burning, Stinging, Peeling, Urticaria, Skin fissures _ Pregnancy Category Note Pregnancy Small amounts of imidazoles may be absorbed systemically following topical and vaginal administration Lactation Excretion in milk unknown; use with caution _ Interaction Antagonism with polyene antibiotics.