Clovir Ointment

Introduction
Clovir Ointment is an antiviral medicine which treats eye infections caused by Herpes simplex virus. It works by preventing the multiplication of the virus on the surface of your eyeball (cornea). This stops the production of new viruses and clears up your eye infection. Clovir Ointment is for external use only. Take it in the dose and duration as advised by your doctor. Wash your hands before and after applying the medicine. Hold the tube close to the eye without touching it. Gently squeeze the tube and place the medicine inside the lower eyelid. It may cause stinging sensation and eye redness immediately following application. However, these side effects are temporary and usually subside on their own. Inform your doctor if they persist for a longer duration. Do not wear contact lenses while using it.

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Uses of Clovir Ointment
Side effects of Clovir Ointment
Common
Eye redness
How to use Clovir Ointment
This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the tube close to the eye without touching it. Gently squeeze the tube and place the medicine inside the lower eyelid.
How Clovir Ointment works
Clovir Ointment is an antiviral medication which treats eye infections caused by Herpes simplex virus. It works by preventing the multiplication of the virus on the surface of your eyeball (cornea). This stops the production of new viruses and clears up your eye infection.
What if you forget to take Clovir Ointment?
If you miss a dose of Clovir Ointment, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Clovir Ointment helps treat eye infections caused by Herpes simplex virus.
Place it inside the lower eyelid five times a day. Do not apply at nighttime.
Continue the tretment for at least 3 days after healing is complete.
It may temporarily cause itching and stinging sensation immediately following application. Inform your doctor if this persists.
Do not wear contact lenses while using Clovir Ointment.
Brief Description
Indication
As 3% Eye oint: Apply 5 times/day until 3rd day of complete healing.
Administration
Probenecid, cimetidine and mycophenolate mofetil may increase the plasma concentration of aciclovir. Increased nephrotoxic effects w/ drugs that affect renal physiology (e.g. ciclosporin, tacrolimus).
Adult Dose
Renal impairment. Pregnancy, lactation. Neurological abnormalities with significant hypoxia, serious hepatic or electrolyte abnormalities. Maintain adequate hydration.
Renal Dose
Activity against HSV types I and II and varicella-zoster virus is due to intracellular conversion of aciclovir to the monophosphate by viral thymidine kinase with subsequent conversion to the diphosphate and active triphosphate by cellular enzymes. This active form inhibits viral DNA synthesis and replication by interfering with viral DNA polymerase enzyme and being incorporated into viral DNA.
Precaution
Herpes simplex keratitis
Pregnancy Category Note
Eye application may produce stinging, superficial punctate keratopathy, blepharitis or conjunctivitis.
Interaction
Hypersensitivity.