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Diaset 50

Tablet - 50mg
Generic: Miglitol
10 Tablets (1 Strip)

Original price was: Tk. 151.Current price is: Tk. 136.

Description

Medicine Overview of Diaset 50mg Tablet

Introduction

Diaset 50 is a medicine used to treat type 2 diabetes mellitus. It helps control the high blood sugar levels in your body after each meal. It is used when other similar medicines along with a restricted diet, are unable to control abnormally high blood sugar levels.

Diaset 50 should be taken just before a meal or along with the first mouthful of food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your blood sugar levels. The dose may be increased gradually. Do not stop taking it without consulting your doctor. If you do, your blood sugar levels may increase and put you at risk of serious complications like kidney damage and blindness.

This medicine is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Monitor your blood sugar levels regularly while taking this medicine.

The most common side effects of this medicine include skin rash, flatulence (gas), stomach pain, and diarrhea. Please consult your doctor if these bother you or do not go away.

This medicine by itself does not cause hypoglycemia (low blood sugar levels). However, when used in combination with other diabetes medicines (especially insulin or sulphonylureas), it can lead to hypoglycemia (low blood sugar levels). Such episodes of hypoglycemia should be treated by taking plain glucose. Table sugar or common sugar will not help correct low blood sugar levels if you are taking this medicine.

Before taking it, let your doctor know if you have any kidney or liver problems. Do not take this medicine if you have ulceration or inflammation in the bowel (eg. ulcerative colitis or Crohn’s disease). Pregnant or breastfeeding women should also consult their doctor before taking it. Please tell your doctor about all the other medicines you are taking to make sure you are safe. Avoid excessive alcohol intake while taking this medicine as it may increase the risk of hypoglycemia (low blood sugar levels).

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Uses of Diaset 50
  • Type 2 diabetes mellitus
Side effects of Diaset 50
Common
  • Skin rash
  • Flatulence
  • Abdominal pain
  • Diarrhea
How to use Diaset 50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Diaset 50 is to be taken with food.
How Diaset 50 works
Diaset 50 is an anti-diabetic medicine. It inhibits the intestinal enzymes responsible for breaking complex sugars into simple sugars such as glucose. This prevents blood glucose levels from rising very high immediately after meals.
What if you forget to take Diaset 50?
If you miss a dose of Diaset 50, skip it and continue with your normal schedule. Do not double the dose.
Quick Tips
  • Diaset 50 lowers your post-meal blood sugar levels. Therefore, it should be taken before meals.
  • Side effects such as stomach pain, gas, and diarrhea may occur during the first few weeks of treatment but should get better with time.
Brief Description
Indication
Type 2 DM
Administration
Should be taken with food. Take w/ 1st bite of each main meal.
Adult Dose

Oral
Type 2 diabetes mellitus
Adult: Initially, 25 mg tid. Increase if necessary after 4-8 wk to 50 mg tid and continue for 3 mth. Max: 100 mg tid.

Hepatic Impairment
No admustment necessary

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Child Dose

Safety & efficacy not established

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Renal Dose

Renal Impairment
Mild-moderate impairment: No dosage adjustment

Severe impairment: Not recommended

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Contraindication
Patient w/ diabetic ketoacidosis, inflammatory bowel disease, colonic ulceration, partial intestinal obstruction or predisposition to this condition, chronic intestinal diseases associated w/ marked disorders of digestion or absorption and co-existing conditions that may deteriorate as a result of increased intestinal gas formation.
Mode of Action
Miglitol reversibly inhibits membrane-bound intestinal ?-glucosidase enzymes which hydrolyse oligosaccharides and disaccharides to glucose and other monosaccharides in the small intestinal brush border. It delays carbohydrate breakdown, glucose absorption and reduces postprandial hyperglycaemia.
Precaution

Patient exposed to stress (e.g. fever, trauma, infection, surgery). Renal impairment. Pregnancy and lactation. Patient Counselling Adhere to diet and exercise regimen. Monitoring Parameters Periodic monitoring of blood glucose tests. Measure glycosylated Hb to monitor long term glycaemic control.

Lactation: Enters slightly into breast milk; nor recommended

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Side Effect

>10%
Flatulence (42%),Diarrhea (29%),Abdominal pain (12%)

1-10%
Rash (4.3%)

Frequency Not Defined
Low serum iron

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Interaction
Concomitant use w/ insulin increases the risk of hypoglycaemia. Intestinal adsorbents (e.g. charcoal) and carbohydrate-splitting digestive enzyme supplements (e.g. amylase, pancreatin) may reduce glycaemic effects. May significantly reduce the bioavailability of ranitidine and propranolol.
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