Medicine Overview of E-400 200mg Tablet
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Indication
Cardiovascular disease, Male infertility, Diabetes, Obesity, Vitamin E deficiency, Peripheral neuropathy, Macular Degeneration
Adult Dose
Oral
Adult: Betterment of Cardiovascular health: 400 mg – 800 mg / day
Deficiency syndrome in adults: 200 mg – 400 mg / day
Thalassemia: 800 mg / day
Sickle-cell anemia: 400 mg / day
Betterment of Skin & Hair: 200 mg – 400 mg / day.
Chronic cold in adults: 200 mg / day
Adult: Betterment of Cardiovascular health: 400 mg – 800 mg / day
Deficiency syndrome in adults: 200 mg – 400 mg / day
Thalassemia: 800 mg / day
Sickle-cell anemia: 400 mg / day
Betterment of Skin & Hair: 200 mg – 400 mg / day.
Chronic cold in adults: 200 mg / day
Child Dose
Oral
Deficiency syndrome in children: 200 mg / day
Deficiency syndrome in children: 200 mg / day
Contraindication
There is no absolute contraindication except known hypersensitivity to vitamin E.
Mode of Action
Vitamin E plays a role in protecting red blood cells against hemolysis; has protective effects against free radicals on polyunsaturated fatty acids found in cell membranes; plays a role in preventing oxidation of vitamin A and C.
Precaution
Vitamin E may enhance the anticoagulant activity of anticoagulant drugs.
Side Effect
Fatigue,Headache,Flatulence,Diarrhea,Blurred vision,Necrotizing enterocolitis (infants),Increased serum creatinine,Increased risk of hemorrhagic stroke,Recent evidence suggests that Vitamin E may suppress action of other antioxidants
Interaction
Colestyramine, colestipol, and orlistat may interfere with vitamin E absorption. High doses of vitamin E potentiates the anticoagulant action of warfarin. Large doses of vitamin E may impair response to iron supplementation.
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