Medicine Overview of Fluclox 250mg Capsule
Fluclox 250 is an antibiotic used to treat a variety of bacterial infections. It is effective in infections of the throat, ear, nasal sinuses, respiratory tract, skin and soft tissue, bones and joints and blood.
Fluclox 250 is a penicillin-type of antibiotic, which mainly fights and stops the growth of the gram-positive type of bacteria. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. This medicine should be used regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication. Before taking this medicine, inform your doctor if you are allergic to penicillin or penicillin-type of medicine.
Nausea, vomiting, diarrhea and local pain, swelling, redness at the site of injection may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision.
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- Bacterial infections
- Nausea
- Vomiting
- Diarrhea
- Allergic reaction
- Injection site reactions (pain, swelling, redness)
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You have been prescribed Fluclox 250 for the treatment of bacterial infections.
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It is given by an injection into a vein or muscle, or via a drip into a vein.
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Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
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Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn’t stop or if you find blood in your stools.
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Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.
Should be taken on an empty stomach. Take on an empty stomach ½-1 hr before meals.
Reconstitution: Dissolve 250-500 mg in 5-10 mL water for inj or 1 g in 15-20 mL water for inj. For IV infusion, further dilute in suitable IV fluids (e.g. water for inj, NaCl 0.9%, glucose 5%, NaCl 0.18% w/ glucose 4%).
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Adults (including elderly patients):
Oral:
250-500mg 3-4 times a day.
Intravenous
IV 0.25-1 g 4 times/day, may double in severe cases. Up to 8 g/day in 3-4 divided doses may be given for osteomyelitis.
Up to 8 g/day in 4 divided doses for endocarditis in patients weighing <85 kg and 12 g/day in 6 divided doses for patients weighing >85 kg.
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Children have been given doses of 12.5-25 mg/kg body weight 4 times a day.
Intravenous
2-10 years: Half of adult dose
Under 2 years: One fourth of adult dose
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Renal impairment:
CrCl (ml/min)
<10 Dosage adjustment may be necessary.
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Hypersensitivity reactions including urticaria; fever; joint pains; rashes; angioedema; serum sickness-like reactions; haemolytic anaemia; interstitial nephritis; neutropenia; thrombocytopenia; CNS toxicity including convulsions; diarrhoea; antibiotic-associated colitis; hepatitis, cholestatic jaundice; agranulocytosis; phlebitis (IV infusion).
Potentially Fatal: Anaphylaxis. Stevens-Johnson syndrome
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