Fructose 10 IV

Indication
Carbohydrate nutrient in diabetic patients, Fluid replacement, Caloric feeding
Adult Dose
It should not exceed 0.5-1 g/kg body weight per hour. The usual recommended flow rate for adult is 30-75 drops per minute infused intravenously.

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Contraindication
Contraindicated in certain inborn errors of fructose metabolism, methyl alcohol poisoning, hyperuricemia, liver failure, and lactic acidosis.
Mode of Action
Hyperosmolar carbohydrate solutions have a direct effect on the GI tract wall, resulting in reduced GI smooth muscle contraction.
Precaution
It should be given with caution to patients with impaired kidney function or severe liver damage. Infusion of fluid should be immediately discontinued if rigor arises for any reason during the process. Do not use if the solution is cloudy, contains particles, or after expiry date.
Side Effect
Intravenous administration may cause lactic acidosis and hyperuricemia. The rapid infusion results in facial flushing, abdominal pain and sweating.