Glycovent

Indication
Maintenance bronchodilator treatment to relieve symptoms in adult patients with, chronic obstructive pulmonary disease (COPD).
Adult Dose
Inhalation The recommended dosage of Glycopyrronium inhalation: One capsule once daily with the ConviHaler device at the same time of day.

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Contraindication
Hypersensitivity to the active substance or to any of the excipients.
Mode of Action
Glycopyrronium is a long-acting, specific antimuscarinic agent, in clinical medicine often called an anticholinergic. It has a similar affinity to the subtypes of muscarinic receptors M1 to M5. In the airways, inhibition of M3-receptors at the smooth muscle results in relaxation.
Precaution
Glycopyrronium should not be used for the initial treatment of acute episodes of bronchospasm, i.e. rescue therapy. Immediate hypersensitivity reactions may occur after administration of Glycopyrronium inhalation powder. As with other anticholinergic drugs, Glycopyrronium should be used with caution in patients with narrow-angle glaucoma, prostatic hyperplasia or bladder-neck obstruction.
Side Effect
Inhaled medicines may cause inhalation-induced bronchospasm, dehydration, dry mouth, constipation, dizziness, insomnia, skin and subcutaneous tissue disorders, immune system disorders.
Pregnancy Category Note
There is a limited amount of data from the use of Glycopyrronium in pregnant women. Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity at clinically relevant doses.