Icid

Indication
Conjunctivitis, Blepharitis, Ocular infections
Adult Dose
Ophthalmic Ocular infections Adult: Apply eye drops into the affected eye/s. May be used up to tid.

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Contraindication
Hypersensitivity; infants <2 mth. _ Mode of Action Sulfacetamide has bacteriostatic effect on a wide range of gram-positive and gram-negative organisms. It interferes with nucleic acid synthesis thus blocking conversion of PABA to the coenzyme dihydrofolic acid. Precaution Elderly. History of allergy or asthma; G6PD deficiency; renal and hepatic impairment. Prolonged therapy requires CBC and urinalysis with microscopic examination. Maintain adequate fluid intake. Pregnancy, lactation. Side Effect Burning, stinging, conjunctivitis, corneal ulcers, irritation, conjunctival hyperaemia. Systemic absorption from inflamed conjunctiva. Potentially Fatal: Stevens-Johnson syndrome. _ Interaction Action antagonised by PABA and procaine group of local anaesthetics. PABA present in purulent eye exudates can competitively inhibit the action of sulphacetamide.