Medicine Overview of Liftear 5% Drop
বাংলা
English
Indication
Dry Eye Disease
Administration
Ophthalmic Administration
Drops are in single-use containers; discard the single-use container immediately after using in each eye
Drops are in single-use containers; discard the single-use container immediately after using in each eye
Remove contact lenses before instilling eye drops; may be reinserted 15 minutes following administration
Adult Dose
Eye drop
Dry Eye Disease
Indicated for treatment of the signs and symptoms of dry eye disease (DED)
Dry Eye Disease
Indicated for treatment of the signs and symptoms of dry eye disease (DED)
Instill 1 gtt q12hr into each eye
Child Dose
<17 years: Safety and efficacy not established
Mode of Action
The exact mechanism in dry eye disease is not known Binds to the integrin lymphocyte function-associated antigen-1 (LFA-1), a cell surface protein bound on leukocytes, and blocks the interactions of LFA-1 with its cognate ligand intercellular adhesion molecule-1 (ICAM-1) ICAM-1 may be overexpressed in corneal and conjunctival tissues in dry eye disease; LFA-1/ICAM-1 interaction can contribute to the formation of an immunological synapse resulting in T-cell activation and migration to target tissues In vitro studies demonstrated that lifitegrast may inhibit T-cell adhesion to ICAM-1 in a human T-cell line and may inhibit secretion of inflammatory cytokines in human peripheral blood
Side Effect
>10%
Instillation site irritation (5-25%)
Instillation site irritation (5-25%)
Dysgeusia (5-25%)
Reduced visual acuity (5-25%)
1-10%
Blurred vision (1-5%)
Conjunctival hyperemia (1-5%)
Eye irritation (1-5%)
Headache (1-5%)
Increased lacrimation (1-5%)
Eye discharge (1-5%)
Eye discomfort (1-5%)
Eye pruritus (1-5%)
Sinusitis (1-5%)
Pregnancy Category Note
Pregnancy
There are no available data regarding use in pregnant women to inform any drug-associated risks
There are no available data regarding use in pregnant women to inform any drug-associated risks
Lactation
There are no data on the presence of lifitegrast in human milk; systemic exposure to lifitegrast from ocular administration is low
Reviews
Clear filtersThere are no reviews yet.