Medicine Overview of Liveric 300mg Tablet
Liveric 300 is a medicine used to dissolve certain types of gallstones, to prevent them from forming and to treat a type of liver disease called primary biliary cirrhosis. It is a bile acid which helps break down cholesterol which has formed into stones in your gallbladder.
Liveric 300 should be taken after a meal with a glass of milk or water. The dose will depend on what you are being treated for and your body weight. It would be best to swallow it whole. This medicine needs to be taken regularly to get the most benefit and you may have to take it for several months or longer, so try to get into a routine. Keep using it as prescribed even if your symptoms disappear. Even if the gallstones completely dissolve, the treatment should still be continued for several weeks or months.
The most common side effects are diarrhea, stomach upset or pain, nausea, dizziness, back pain or hair loss. Not everyone gets side effects. If you are worried about them, or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment.
Before taking this medicine, you should tell your doctor if you have an inflammation of the gallbladder or bile ducts, you get frequent cramp-like pain in your upper abdomen, you have been coughing up blood or you have gained weight rapidly. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor all other medicines you are taking. Women who use this medicine for dissolving gallstones should stop using the birth control pill because the hormones present in it can increase the production of gallstones. During the treatment, you may need ultrasound scans, or frequent blood tests to check your liver function.
- Primary biliary cirrhosis
- Gallbladder stones
- Abdominal pain
- Diarrhea
- Hair loss
- Itching
- Nausea
- Rash
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Liveric 300 should be taken after a meal with a glass of milk or water.
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Eat a healthy diet, exercise regularly and avoid alcohol intake.
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Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
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Your doctor may monitor your liver function and bilirubin levels every month for next 3 months after the start of therapy, and every 6 months thereafter.
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Do not stop taking the medication without talking to your doctor.
Oral
Dissolution of cholesterol-rich gallstones
Adult: 8-12 mg/kg once daily at bedtime or in 2 divided doses continued for 3-4 mth after radiological disappearance of gallstones. Duration of treatment: Up to 2 yr.
Obese patients: Up to 15 mg/kg daily.
Primary biliary cirrhosis
Adult: 10-16 mg/kg daily in 2-4 divided doses, may be taken once daily in the evening after the 1st 3 mth.
Prophylaxis of gallstones in patients undergoing rapid weight loss
Adult: 300 mg bid.
Non-alcoholic fatty liver disease: 13-15 mg/kg/day;
Excessive diatery intake of calories and cholesterol should be avoided. Liver function tests and bilirubin levels should be monitored every month for three months after start of therapy. 50% of successfully treated patients will develop further gallstones within 10 yr. Pregnancy and lactation. Monitoring Parameters Monitor LFTs mthly for the 1st 3 mth and every 6 mth thereafter.
Lactation: unknown if excreted in breast milk; use caution
>10%
Headache,Dizziness,Diarrhea,Dyspepsia,Nausea/vomiting,Back pain,Upper respiratory tract infection
1-10%
Alopecia,Rash,Hyperglycemia,Flatulence,Peptic ulcer,Urinary tract infection,Leukopenia,Thrombocytopenia,Cholecystitis
>1%
Fatigue,Abdominal pain,Thrombocytopenia,Pruritus,Angioedema,Peripheral edema,Biliary pain
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