Medicine Overview of Locaine Inj 2% Injection
Locaine Inj is a local anesthetic used to temporarily numb certain areas of the body. It is used as an anesthetic lubricant to insert of instruments in the human body for medical procedures (e.g., catheters). It is also used for the treatment of symptoms of painful inflammation of the urethra and bladder.
The most common side effects of this medicine include redness, rash, burning and itching on the area of application. These are usually mild and short-lived. Consult your doctor if any of the side effects persist or worry you.
Before using it, tell your doctor if you have liver disease or are taking medicines for heart rhythm problems. Although medicines used on the skin are not normally affected by other medicines you should let your doctor know if you are taking any other medicines to be safe. Ask your healthcare team for advice if you are pregnant or breastfeeding.
- Local anesthesia (Numb tissues in a specific area)
- Allergic reaction
- Application site reactions (burning, irritation, itching and redness)
-
Locaine Inj is prescribed to relieve itching and pain caused by scrapes, burns, rashes, bites and eczema.
-
Apply it over the affected area with a clean fingertip, three to four times a day or as directed by your doctor.
-
Do not apply it to broken or infected areas of skin, face, eyes or eyelids unless instructed to by your doctor.
-
Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
-
Avoid contact with eyes, mouth, and nose. In case of accidental contact, rinse thoroughly with water.
-
Consult your doctor if your skin condition has not improved after 2-4 weeks of treatment.
-
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
IV Preparation
Add 1-2 g of lidocaine hydrochloride to 1 L of D5W making 1-2 mg/mL solution; use (using 5-10 mL of 20% inj soln); may also use 400 mg/100 mL in D5W or 800 mg/100 mL in D5W
8 mg/mL concentrations have been recommended for fluid-restricted pts
Intravenous
Ventricular Arrhythmias
1-1.5 mg/kg slow IV bolus over 2-3 minutes
May repeat doses of 0.5-0.75 mg/kg in 5-10 minutes up to 3 mg/kg total
Continuous infusion: 1-4 mg/min IV
Regional Anesthesia (IV)
4 mg/kg
Parenteral
Sympathetic nerve block
Adult: As 1% soln: 50 mg for cervical block or 50-100 mg for lumbar block.
Epidural
Epidural anaesthesia
Adult: 2-3 mL administered for each dermatome to be anaesthesised.
Recommended doses are: Lumbar epidural 250-300 mg (as 1% soln) for analgesia and 225-300 mg (as 1.5% soln) or 200-300 mg (as 2% soln) for anaesth;
for thoracic epidural: 200-300 mg (as 1% soln).
For obstetric caudal analgesia: 200-300 mg (as 1% soln);
for surgical caudal anaesth: 225-300 mg (as 1.5% soln).
For continuous epidural or caudal anaesth, not to repeat max doses more frequently than 1.5 hrly.
Peripheral nerve block
Adult: As 1.5% soln: For brachial plexus block: 225-300 mg.
As 2% soln: For dental nerve block: 20-100 mg.
As 1% soln: For intercostal nerve block: 30 mg; for paracervical block: 100 mg on each side, repeated not more frequently than every 90 min; for paravertebral block: 30-50 mg; for pudendal block: 100 mg on each side.
As 4% soln: For retrobulbar block: 120-200 mg.
Intraspinal
Spinal anaesthesia
Adult: As hyperbaric soln of 1.5% or 5% lidocaine in 7.5% glucose soln.
Normal vaginal delivery: Up to 50 mg (as 5% soln) or 9-15 mg (as 1.5% soln).
Caesarian operation: Up to 75 mg (as 5% soln).
Other surgical procedures: 75-100 mg.
Hepatic impairment: Dosage reduction may be needed.
Ventricular Arrhythmias
Bolus: 0.5-1 mg/kg IV/IO/ET, not to exceed 100 mg; follow with continuous infusion; if delay between bolus and start of infusion is >15 minutes, administer a second bolus q5-10min to 5 mg/kg, THEN
Continuous infusion: 20-50 mcg/kg/min IV
Hepatic or renal impairment; CHF and following cardiac surgery; bradycardia; respiratory depression; porphyria; elderly or debilitated patients; pregnancy.
Lactation: crosses into breast milk, use caution
Common
Cardiovascular: Hypotension
Dermatologic: Edema, erythema at injection site, petechiae, skin irritation
Gastrointestinal: Constipation, Nausea, vomiting
Neurologic: Confusion, dizziness, headache, paresthesia, somnolence, tremor
Other: Irritation symptom, Topical products; ie, erythema, edema
Serious
Cardiovascular: Cardiac arrest, cardiac dysrhythmia
Hematologic: Methemoglobinemia
Neurologic: Seizure
Anaphylactoid reactions
Malignant hyperthermia
Potentially Fatal: Hypotension and bradycardia leading to cardiac arrest; anaphylaxis.
Reviews
Clear filtersThere are no reviews yet.