Lotenate Ophthalmic

Introduction
Lotenate Ophthalmic belongs to a group of medicine called steroids. It is used for treatment of redness and swelling in the eyes caused by infection or allergy. It provides relief from redness, itchiness and soreness by preventing the release of substances in the body that cause inflammation. Never use Lotenate Ophthalmic if the seal is broken before you use it for the first time. Wash your hands before using it. Make sure you remove contact lenses if you wear them and wait for at least 15 minutes after application before putting them back. You should not discontinue using the medicine unless your doctor tells you so. Stopping the medication before time may allow the bacteria to continue their growth, which may result in return of the infection. It may cause eye irritation, burning sensation, and watery eyes. These are usually temporary and resolve with time. It may also blurred your vision or cause other changes in sight for a short time, do not drive or operate other machines until your vision is clear. If you are pregnant or breastfeeding, you should consult with your doctor before using this medicine.

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Uses of Lotenate Ophthalmic
Redness and swelling in the eye
Side effects of Lotenate Ophthalmic
Common
Eye irritation
Watery eyes
Burning sensation
How Lotenate Ophthalmic works
Lotenate Ophthalmic is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the eye red, swollen and itchy.
What if you forget to take Lotenate Ophthalmic?
If you miss a dose of Lotenate Ophthalmic, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Your doctor has prescribed Lotenate Ophthalmic to treat redness and swelling (inflammation) of the eye.
Do not use Lotenate Ophthalmic for more than the prescribed duration as it may cause glaucoma or secondary infection.
Do not touch the tip of the dropper to any surface, or to your eye, to avoid contaminating the eye drops.
Apply pressure on the corner of the eye (close to the nose) for about 1 minute immediately after instilling the drop.
Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
Stinging sensation may occur for 1-2 mins. Notify your doctor if it persists for longer.
If you wear soft contact lenses, remove them before putting in these eye drops and wait at least 15 minutes before putting your lenses back in.
Make sure to use within 4 weeks of opening the bottle.
Side effects such as mood changes or stomach problems can happen when you start taking Lotenate Ophthalmic. Inform your doctor if this bothers you.
Do not stop taking Lotenate Ophthalmic suddenly without talking to your doctor first as it may worsen your symptoms.
Brief Description
Indication
Allergic conjunctivitis, Ocular inflammation
Adult Dose
Ophthalmic Steroid-Responsive Inflammatory Conditions Indicated for the treatment of steroid-responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe (eg, allergic conjunctivitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivitides) Adult: Eye drops: Apply 1-2 drops into conjunctival sac of the affected eye(s) QID; if necessary, may increase dose up to 1 drop every hour during initial treatment within the first week Re-evaluate if signs and symptoms do not improve after 2 days Postoperative Ocular Inflammation Adult: Eye drops: Apply 1-2 drops into the conjunctival sac of the operated eye(s) QID beginning 24 hr after surgery and continuing throughout the first 2 weeks of the postoperative period Eye Ointment: Apply small amount (0.5-inch ribbon) into conjunctival sac(s) QID beginning 24 hr after surgery and continue throughout the first 2 weeks of the postoperative period

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Child Dose
Safety and efficacy not established
Contraindication
Lotepro is also contraindicated in individuals with known or suspected hypersensitivity to any of the ingredients of this preparation and to other corticosteroids. Viral infections of the cornea and conjunctiva; mycobacterial eye infection; fungal infections of ocular structures.
Mode of Action
Loteprednol is a synthetic nonfluorinated glucocorticoid. It stimulates the production of lipicortins, proteins that modulate the activity of prostaglandins and leukotrienes.
Precaution
May mask and exacerbate existing ocular infection. Re-evaluate patients if symptoms do not improve after 2 days. Glaucoma; may delay healing after cataract surgery. Monitor intraocular pressure (prolonged use).
Side Effect
Local reactions (e.g. blurred vision, burning, itching, dry eye), photophobia, headache, rhinitis, pharyngitis. Prolonged use may increase IOP, which may be associated with possible development of glaucoma and infrequent optic nerve damage; posterior sub-capsular cataract formation and perforation of the globe where there is thinning of the cornea or sclera.