Lutisone 0.005%

Introduction
Lutisone 0.005% belongs to a group of medicines called steroids. It is used for treatment of skin conditions with inflammation and itching such as eczema, dermatitis, and psoriasis. It provide relief from pain, swelling, redness, and itching in several skin problems. Lutisone 0.005% is only meant for external use and should be used as advised by your doctor. You should normally wash and dry the affected area before applying a thin layer of the medicine. Avoid any contact with your eyes, nose, or mouth. Rinse it off with plenty of water in case of accidental contact. Avoid covering the treated area with airtight dressings such as bandages unless directed by a doctor. Using of the medicine may cause itching or burning sensation, irritation, redness, and swelling at the site of application. These side effects are temporary and usually go away with time. However, if they persist or worsen, let your doctor know. Pregnant and breastfeeding mothers should consult their doctors before using this medicine. It should not be used in children below 1 year of age.

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Uses of Lutisone 0.005%
Skin conditions with inflammation & itching
Side effects of Lutisone 0.005%
Common
Application site reactions (burning, irritation, itching and redness)
How to use Lutisone 0.005%
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and gently massage the ointment.
How Lutisone 0.005% works
Lutisone 0.005% is a steroid medicine. It works by blocking the production of certain chemical messengers that make the skin red, swollen and itchy due to skin conditions such as atopic eczema, allergic contact dermatitis, and psoriasis.
Quick Tips
You have been prescribed Lutisone 0.005% for treating itchy, red rashes and skin irritation associated with skin conditions such as atopic eczema, allergic contact dermatitis, and psoriasis among others.
Don’t use it more often or for longer than advised by your doctor.
Don’t apply it to broken or infected areas of skin, face, eyes or eyelids.
Don’t cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
If you think the area of skin you are treating has become infected you should stop using Lutisone 0.005% and consult your doctor.
Consult your doctor if your skin condition has not improved after two weeks of treatment.
Brief Description
Indication
Psoriasis, Eczema, Corticosteroid-responsive dermatoses
Adult Dose
Topical ointment Atopic Dermatitis, Corticosteroid-responsive Dermatoses Apply a thin film to the affected skin areas once or twice daily. Rub in gently. Reassess diagnosis if no improvements within 2 weeks

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Child Dose
Topical ointment Atopic Dermatitis, Corticosteroid-responsive Dermatoses Child > 1 year: Apply a thin film to the affected skin areas once or twice daily.

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Contraindication
Fluticasone Propionate ointment is contraindicated in those patients with a history of hypersensitivity to any of the components in the preparation.
Mode of Action
Fluticasone Propionate is a synthetic, trifluorinated corticosteroid that provides anti-inflammatory activity. It binds to glucocorticoid receptor and inhibits the migration of inflammatory mediator & cells (histamine, leukotrienes, mast cells, eosinophils etc).

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Precaution
Fluticasone Propionate ointment may cause local cutaneous adverse reactions. If irritation develops, Fluticasone Propionate ointment should be discontinued. Fluticasone Propionate ointment should not be used in the presence of preexisting skin atrophy and should not be used where infection is present at the treatment site. This should not be used in the treatment of rosacea and perioral dermatitis. Lactation: Excretion in milk unknown; use with caution

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Side Effect
1-10% Pruritus (2.9%),Dryness (1.2%),Skin irritation: (3%),Eczema (1%),Telangiectasia (2-5%),Numbness of fingers (1%) <1% Burning,Folliculitis,Acneiform lesions,Urticaria,Hypertrichosis,Lightheadedness,Viral,Warts,Impetigo,Skin infection Frequency Not Defined Striae,Pigmentation changes,HPA suppression (with higher potency used >2 wk),Erythema,Cushing syndrome,Sepsis,Hemorrhage reported,Edema/swelling

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Pregnancy Category Note
Pregnancy Category: C Lactation: Excretion in milk unknown; use with caution

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Interaction
May lead to increased plasma concentrations of fluticasone when used with CYP4503A4 inhibitors such as ritonavir.