Medicine Overview of Meczin 50
Meczin 50 is an antihistamine medicine used to treat nausea, vomiting and vertigo associated with motion sickness.
Meczin 50 should be taken with or without food, but take it at the same time every day to get the most benefit. If you are travelling, then take it one hour before travelling. It should be taken as your doctor’s advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. In case, you have missed any doses than it is better to take the next dose as soon as you remember it. However, you should never take a double dose.
Sleepiness is the most common side effect of this medicine. Avoid driving or attention-seeking activity. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. In some cases, it may cause dryness of mouth, so it is advised to drink more water, always carry sugar candy or maintain oral hygiene.
Before taking this medicine, let your doctor know if you have glaucoma or have any gastro related issues or have high blood pressure. Inform your doctor if you are pregnant, or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Generally, it is advised to avoid alcohol while on treatment.
- Motion sickness
- Vertigo
- Sleepiness
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Meczin 50 can increase the effects of other CNS depressants (alcohol, barbiturates) medicine.
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If you are using Meczin 50 for motion sickness, it should be taken an hour before your travel.
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Avoid consuming alcohol when taking the Meczin 50, as it may cause excessive sleepiness or drowsiness.
Oral
Motion sickness
Adult: 25-50 mg 1 hr before travelling and repeat 24 hrly if needed.
Vertigo and vestibular disorders
Adult: 25-100 mg daily in divided doses. Discontinue if there is no response after 1-2 wk of treatment.
Nausea and vomiting
25-50 mg daily
Radiation sickness:
50 mg administered 2-12 hours prior to radiation treatment.
Prevention of nausea and vomiting associated with emergency contraceptive pill (ECP) :
25-50 mg, 1 hour before first ECP dose; repeat if needed in 24 hours.
Oral
<12 years: Safety and efficacy not established
Motion Sickness
>12 years: 12.5-50 mg PO given 1 hour before travel and then daily PRN
Vertigo
>12 years: 25-100 mg/day PO in single daily dose or divided q6-12hr
Patients should be warned that Meclizine Hydrochloride may impair their ability to perform hazardous activities requiring mental alertness or physical coordination (e.g., operating machinery, driving a motor vehicle). Patients should avoid alcoholic beverages while taking this drug. Due to its potential anticholinergic action, this drug should be used with caution in patients with asthma, glaucoma or enlargement of the prostate gland.
Lactation: Not known if excreted in milk; use caution

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