Mendil

Indication
Relieves cough, sneezing, nasal congestion due to throat & bronchial irritation as may occur w/, common cold, allergy, bronchitis, inhaled irritants.

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Administration
May be taken with or without food.
Adult Dose
Oral For the treatment of cough & other congestive symptoms associated with the common cold. Adult 1-2 tsf every 4 or 6 hourly

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Child Dose
Oral For the treatment of cough & other congestive symptoms associated with the common cold. Childn >1 yr ½-1 tsf 4 or 6 hourly

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Contraindication
Hypersensitivity
Mode of Action
Diphenhydramine is a potent antihistamine and antitussive with anticholinergic and sedative properties. Recent experiments have shown that the antitussive action is discrete from H1-receptor blockade and is located in the brain stem. Levomenthol has mild local anaesthetic and decongestant properties.

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Precaution
Should be used with caution in patients with narrow-angle glaucoma or symptomatic prostatic hypertrophy. May impair ability to drive or operate machinery.
Side Effect
Diphenhydramine may cause drowsiness, dizziness, gastrointestinal disturbance; dry mouth nose and throat; difficulty in urination or blurred vision. Less frequently it may cause palpitations, tremor, convulsions or paraesthesia. Hypersensitivity reactions have been reported, in particular, skin rashes, erythema, urticaria and angiodema. Adverse reactions to levomenthol at the low concentration present are not anticipated.

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Interaction
Phenothiazine derivatives, benzodiazepines, MAOIs, TCAs. This product contains diphenhydramine and therefore may potentiate the effects of alcohol, codeine, antihistamines and other CNS depressants. As diphenhydramine possesses some anticholinergic activity, the effects of anticholinergics (e.g. some psychotropic drugs and atropine) may be potentiated by this product. This may result in tachycardia, dry mouth, gastrointestinal disturbances (e.g. colic), urinary retention and headache.

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