Metalone Plus

Indication
Keratitis, Allergic and inflammatory conditions of the eye, Iridocyclitis, Iritis, Acute & chronic conjunctivitis, Scleritis, Episcleritis, Myositis. Post-op conditions after strabotomy, Cataract & glaucoma operations

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Contraindication
This medication is contraindicated in following cases- • Viral infection of cornea & conjunctiva caused by Herpes simplex etc • Fungal infection of the cornea & conjunctiva • Tuberculous infections • Ulcerous processes of the cornea • Hypersensitivity to any ingredients of this formulation.

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Mode of Action
Fluorometholone suppresses the migration of polymorphonuclear leukocytes and reversal of increased capillary permeability thus decreasing inflammation. May stimulate alpha-adrenergic receptors in the arterioles of the conjunctiva; produces vasoconstriction. May produce mydriasis when applied to the conjunctiva, but this effect is usually minimal with the concentrations used as ocular decongestants.

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Precaution
• Prolonged use in pregnant women and infants should be avoided • This medication should be used with caution in patients under treatment with MAO inhibitors • Do not apply while wearing soft contact lenses. The lenses should be removed before application of the drops and not reinserted earlier than 15 minutes after use. • Shake well before use.

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Side Effect
Mild burning sensation, reversible increase in intra ocular pressure (IOP), reactive hyperemia/rebound effect, cataract & corneal defects, glaucoma, systemic effects (chronic use).

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