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Mezest 160

Name: Mezest 160
SKU: SKU-BjZsHb21
Availability: InStock

Tablet - 160mg

Beacon Pharmaceuticals PLC

Generic: Megestrol Acetate

6 Tablets (1 Strip)

Original price was: Tk. 540.Current price is: Tk. 481.

Description

Medicine Overview of Mezest 160mg Tablet

Introduction

Mezest 160 is used to treat breast cancer and endometrial cancer. It specifically helps treat breast and endometrial cancer that are hormone dependent. It may also be used for treating low appetite and weight loss in patients with advanced cancer or HIV.

Mezest 160 should be taken with or without food, preferably at a fixed time each day to ensure consistent levels of medicine in the body. This medicine is not used for pregnant or breastfeeding women. It may cause side effects like high blood pressure and increased blood sugar levels but they are temporary. However, if these persists, consult with the doctor.

Uses of Mezest 160

Breast cancer
Endometrial cancer

Side effects of Mezest 160

Common

Increased appetite
Weight gain
Hot flashes
High blood pressure
Constipation
Increased glucose level in blood

How to use Mezest 160

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mezest 160 may be taken with or without food, but it is better to take it at a fixed time.

How Mezest 160 works

Mezest 160 is a progestin (female hormone). It works in patients with breast cancer and endometrial cancer by affecting female hormones involved in cancer growth. It causes weight gain by increasing appetite.

Quick Tips

Mezest 160 is used to treat women with certain hormone-dependent cancers such as breast cancer and endometrial cancer.

It may also be used for treating appetite and weight loss in people with advanced cancer or AIDS.

You may have to take it for atleast 2 months before you notice any changes in your appetite.

Your doctor might do regular blood tests to check your hormones and blood sugar levels while you are taking this medicine.

Do not take Mezest 160 if you are pregnant or breastfeeding.

Inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision. These could be symptoms of a blood clot in a vein.

Do not stop taking the medicine suddenly without talking to your doctor first.

Brief Description

Indication

Contraception, Breast carcinoma, Endometrial carcinoma, Anorexia and Cachexia

Administration

Should be taken with food.

Adult Dose

Oral
Palliative treatment of breast carcinoma
Adult: 40 mg 4 times daily or 160 mg once daily.

Palliative treatment of endometrial carcinoma
Adult: 40-320 mg daily in divided doses. evaluate efficacy after 2 months of treatment; up to 800 mg/day may be used

Anorexia and cachexia in patients with cancer or AIDS
Adult: Initial: 800 mg daily. Usual range: 400-800 mg daily.

Renal Dose

Renal impairment: Use with caution; in normal renal function, 57-78% is excreted in urine within 10 days

Contraindication

Pregnancy and lactation. Severe hepatic impairment.

Mode of Action

Megestrol is a progestogen used as an antineplastic and appetite stimulant. The mechanism of it’s antineoplastic effects is not known but may be due to inhibition of oestrogen synthesis, modulation of other steroid hormones and/or a direct cytotoxic effect on tumour cells.

Precaution

History of thrombophlebitis, mild to moderate hepatic impairment, risk of fluid retention, history of depression, diabetes, hypertension, renal or cardiac dysfunction.

Lactation: Not safe; do not nurse

Side Effect

Common
Hypertension,Insomnia, mood swings
Rash, sweating,Amenorrhea, breakthrough bleeding, change in menstrual flow, hot sweats, impotence, spotting
Diarrhea, flatulence, indigestion, nausea, vomiting, weight gain

Serious
Deep vein thrombosis (DVT),Pulmonary embolism,Thrombophlebitis,Anemia,Adrenal insufficiency

Interaction

Concentrations of indinavir may be reduced. Possible reduced efficacy of cisplatin. Warfarin half life may be increased. Megestrol concentration may be decreased by aminoglutethimide and enzyme-inducing drugs.