Mirolast

Indication
Allergic conjunctivitis
Adult Dose
Ophthalmic Prophylaxis of allergic conjunctivitis Adult: As 0.1% ophthalmic solution: Instill 1-2 drops into the affected eye(s) 4 times daily.

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Child Dose
Ophthalmic Prophylaxis of allergic conjunctivitis Child: >3 yr: As 0.1% ophthalmic solution: Instill 1-2 drops into the affected eye(s) 4 times daily.

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Contraindication
Contraindicated in patients with previously demonstrated hypersensitivity to any of the ingredients of this product.
Mode of Action
Pemirolast is a mast cell stabiliser that inhibits the in vivo Type I immediate hypersensitivity reaction. It inhibits chemotaxis of eosinophils into the ocular tissue and blocks the release of mediators. It is also reported to prevent calcium influx into mast cells following antigen stimulation. It has also been used in the treatment of chronic asthma and prophylaxis of allergic rhinitis.
Precaution
Not for treatment of contact lens-related irritation. Contact lens should be removed prior to drug admin and reinserted only at least 10 minutes after application. Safety and efficacy have not been established in children <3 yr. Pregnancy and lactation. Lactation: Distributed in breast milk; caution advised _ Side Effect 1-10% Burning,Dry eyes,Foreign body sensation,Ocular discomfort,Allergy,Bronchitis,Cough,Sneezing,Nasal congestion _