Medicine Overview of Napcon 250mcg+3mg/ml Eye Drop
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Indication
Itchy, Red eyes
Adult Dose
Ophthalmic Ocular allergy Adult: Apply 1-2 drops in the affected eye up to 4 times daily.
Child Dose
Allergic Conjunctivitis <6 years: Not established 6 years or older: Apply 1-2 drops in the affected eye up to 4 times daily.
Contraindication
Hypersensitivity, Angle closure glaucoma.
Mode of Action
Naphazoline, an imidazoline derivative is a sympathomimetic with alpha-adrenergic activity. It produces vasoconstriction. When applied topically to mucous membranes, it reduces swelling and congestion. It is often used in combination with pheniramine, an alkylamine derivative antihistamine, in ophthalmic preparations.
Precaution
Glaucoma, hypertension, CV abnormalities, DM, hyperthyroidism, infection, or injury. Pregnancy and lactation. Avoid in infants and young children <6 yr. Rebound congestion may occur with prolonged use or overuse. Patient to seek medical advice if there is ocular pain, vision changes, worsening of redness or irritation of the eye or symptoms lasts >72 hr. Remove contact lens before use. Lactation: Unknown whether distributed in breast milk, weigh benefits against risks
Side Effect
Blurring of vision, mild stinging and/or irritation, mydriasis and increased or decreased intraocular pressure. Ocular erythema. When used in high doses in elderly, naphazoline may liberate pigment granules from the iris.
Interaction
Increased pressor effects with maprotiline or TCA. Possibility of severe hypertensive reaction with MAOI.
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