Nitaxen PFS

Introduction
Nitaxen PFS is an antiparasitic medication, used in the treatment of diarrhea and worm infections. It inhibits the growth of the parasite and thus treats your infection. Nitaxen PFS should be used in the dose and duration as advised by your doctor. It should be taken with food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned. Some people may experience headache, nausea, fever, hair loss and vomiting as the side effects of this medicine. Please consult your doctor if these do not resolve or persist for a longer duration. You may be monitored with blood tests and liver function tests throughout your treatment.

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Uses of Nitaxen PFS
Diarrhea
Worm infections
Side effects of Nitaxen PFS
Common
Headache
Nausea
Fever
Hair loss
Vomiting
Abnormal liver function tests
Dizziness
Abdominal pain
Vertigo
How to use Nitaxen PFS
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nitaxen PFS is to be taken with food.
How Nitaxen PFS works
Nitazoxanide is an antiparasitic medication. It inhibits the production of certain chemicals and substances essential for energy metabolism and growth of the parasite.
Quick Tips
You have been prescribed Nitaxen PFS to treat a variety of parasitic worm infections.
It should be taken with food.
If you are unable to swallow the whole tablet, it may be crushed or chewed and swallowed with a full glass of water.
It can be harmful to an unborn baby. Do not take it during pregnancy or breastfeeding. Use birth control measures to prevent pregnancy while taking Nitaxen PFS.
Your doctor may monitor your blood counts and liver function before you start taking this medicine and regularly throughout your treatment.
Avoid being near people who are sick or have infections. Inform your doctor if you develop signs of infection.
Do not skip doses and finish the prescribed course, even if you start to feel better. Stopping it early may increase your risk of further infection.
Brief Description
Indication
Giardiasis, Cryptosporidiosis
Administration
Should be taken with food.
Adult Dose
Oral Giardiasis; Cryptosporidiosis Adult: 500 mg every 12 hr for 3 days.

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Child Dose
Oral Giardiasis; Cryptosporidiosis Child: 1-3 yr: 100 mg(5 ml) every 12 hr; 4-11 yr: 200 mg(10ml) every 12 hr; >12 yr: 500 mg every 12 hr. All doses to be taken for 3 days.

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Contraindication
Hypersensitivity.
Mode of Action
Nitazoxanide is an antiprotozoal agent. Both nitazoxanide and its active metabolite (tizoxanide) interfere with the pyruvate:ferredoxin 2-oxidoreductase (PFOR) enzyme-dependent electron transfer reaction which is essential to anaerobic metabolism in susceptible organisms.
Precaution
Renal and hepatic impairment. Pregnancy and lactation. Children <1 yr. _ Side Effect 1-10% Headache (1%),Abdominal pain (8%),Diarrhea (2%),Nausea (3%),Chromaturia (2%),Vomiting (1%) <1% Increased ALT,Anorexia,Appetite increased,Creatinine increased,Diaphoresis,Dizziness,Eye discoloration (pale yellow),Fever,Flatulence,Infection,Malaise,Pruritus,Thinitis,Salivary glands enlarged,Urine discoloration _ Interaction May possibly interact with highly protein-bound drugs e.g. warfarin.