Medicine Overview of Nomigran 100mg Tablet
Nomigran is a prescription medicine used in the treatment of migraine. It relieves the symptoms of migraine and prevents the attack from becoming worse. This medicine helps by narrowing the blood vessels, thereby relieving migraine headaches.
Nomigran may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Do not skip any doses and finish the full course of treatment even if you feel better and if you have missed a dose, take it as soon as you remember. You should continue to take this medicine for as long as doctor advises and do not stop taking it suddenly.
Side effects associated with the use of this medicine include dizziness, weakness, drowsiness, peripheral neuropathy (tingling and numbness of feet and hands) and flushing (sense of warmth in the face, ears, neck and trunk). However, these are usually temporary and usually resolve on their own. Please consult your doctor if these do not subside or worry you.
It may also cause sleepiness in the beginning of your treatment, so do not drive, operate machinery, until you know how this medicine affects you. This medicine may cause changes in your mood and you may feel depressed, therefore, regular monitoring of behavior is important. Pregnant or breastfeeding mothers should consult their doctor before taking this medicine.
Inform your doctor if you are suffering from any heart problems, as the use of Nomigran is contraindicated in some heart diseases. Regular monitoring of blood pressure is required while taking this medicine. Consult your doctor and stop this medicine if you develop severe chest or stomach pain, bloody diarrhea, or significantly high blood pressure, after taking this medicine.
- Migraine
- Dizziness
- Weakness
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Drowsiness
- Peripheral neuropathy (tingling and numbness of feet and hand)
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You have been prescribed Nomigran for treatment of migraine headaches.
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Some tips that may help avoid a migraine attack:
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It may cause sleepiness. Don’t drive or do anything that requires mental focus until you know how it affects you.
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Notify your doctor if your migraine occurs more often after starting the medication.
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Notify your doctor if you have stomach pain, headache, bloody diarrhoea or worsening high blood pressure.
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Inform your doctor if you have a history of heart disease or stroke.
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This medication does not prevent migraine attacks from happening.
Oral
Migraine
Adult: >18 yr: 50-100 mg repeated at 2-hr intervals if migraine recurs. Max: 200 mg/24 hr.
Mild to moderate hepatic impairment: Max single dose: 50 mg.
Severe hepatic impairment: Contraindicated
<18 years: Safety and efficacy not established
Conditions predisposing to seizures, presence of coronary risk factors, cardiac arrhythmias, renal or hepatic impairment, elderly, pregnancy, lactation.
Lactation: Excreted in breast milk at very low levels; minimize infant to potential exposure by avoiding breastfeeding for 8-12 hours after administration
>10%
Injection site reaction (<86%),Paresthesia (5-14%),Dizziness (12%),Warm/hot sensation (11%)
1-10%
Chest discomfort/pressure/tightness (2-5%),Jaw or neck tightness (1-5%),Diaphoresis (2%),Burning sensation (7%),Cold sensation (1%),Dysphagia,Sore throat (3%),Malaise (1%),Abdominal distress (1%)
Frequency Not Defined
Agitation,Cardiac arrhythmia: V-fib/V-tach (rare),Dysuria,Eye irritation,Flushing,MI and coronary artery vasospasm in patients with CAD risk factors (extremely rare),Nasal discomfort,Palpitations,Tingling,Weakness
Potentially Fatal: Cardiac arrhythmias, MI.
Concurrent use increased risk of vasospastic reaction with ergotamine and related compounds.
Potentially Fatal: Increased risk of serotonin syndrome with concurrent use of SSRI, MAOIs or within 14 days of stopping MAOIs. Admin of ergotamine or related compounds within the previous 24 hr.
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