Nyst

Introduction
Nyst is an antifungal medication. It is used in the treatment of fungal skin infections. It kills the fungi that cause skin infections and thus treats the infection. Nyst is for external use only. You should use it in the dose and duration as advised by your doctor. The affected area should be clean and dry before application of the ointment. You must wash your hands thoroughly before and after applying this medicine. To avoid relapse, continue the use of this medicine even if symptoms begin to clear up. Some common side effects include skin irritation, redness or itching at the site of application. Please consult your doctor if these side effects persist for a longer duration. Avoid direct contact of the cream or ointment with your eyes. In case of direct contact, wash your eyes with water and seek immediate medical attention.

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Uses of Nyst
Fungal skin infections
Side effects of Nyst
Common
Application site reactions (burning, irritation, itching and redness)
How to use Nyst
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and gently massage the ointment.
How Nyst works
Nyst is an antifungal medication. It kills fungi by destroying the fungal cell membrane.
What if you forget to take Nyst?
If you miss a dose of Nyst, please consult your doctor.
Quick Tips
Nistin 100000IU Ointment should be applied once or twice a day or as prescribed by your doctor.
Do not use this medicine more often or for longer than advised by your doctor.
Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas.
Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
Inform your doctor if the treated skin area does not improve after 2 weeks of treatment.
Brief Description
Indication
Fungal infections, Oropharyngeal candidiasis, Intestinal candidiasis, Vaginal candidiasis
Administration
May be taken with or without food.
Adult Dose
Oral Oral candidiasis Adult: As oral susp or drop : 100,000-600,000 U (1-6 ml drop) into the mouth 4 times daily. Keep in contact w/ affected area as long as possible. Continue for 48 hr after clinical cure to prevent relapse. Intestinal candidiasis Adult: As tab or oral susp/drop: 500,000 or 1,000,000 U 3-4 times daily. Prophylaxis: 1,000,000 U daily. Vaginal Vulvovaginal candidiasis Adult: insert 1 vaginal tablet into vagina daily at bedtime for 14 days or longer.

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Child Dose
As oral susp or drop Infants: PO: 2 mL/dose, children 4–6 mL/dose, to coat oral mucosa q6h As tab Child: PO: 3–6 tabs/day tid For prophylaxis of oral candidiasis in the newborn the suggested dose is 1 ml (100,000 U) once daily. Administration should be continued for 48 hours after clinical cure to prevent relapse.

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Contraindication
Hypersensitivity.
Mode of Action
Nystatin, a polyene antifungal, binds to ergosterol in the fungal cell membrane. This binding affects the cell wall permeability allowing leakage of cellular contents.
Precaution
Immunocompromised patients. Childn. Pregnancy and lactation. Patient Counselling May damage latex contraceptives (vag). Lactation: Not known if excreted in breast milk; use caution

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Side Effect
Nausea, vomiting, diarrhoea, GI upset, oral irritation and sensitisation. Rarely, rash, urticaria, Stevens-Johnson syndrome, tachycardia, bronchospasm, facial swelling, nonspecific myalgia Vaginal tablet: May damage latex contraceptives (e.g. diaphragms, condoms), additional contraceptive measures should be taken. Localized sensitization.

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Pregnancy Category Note
Pregnancy category: C, ROUTE(S) : Mouth/Throat / PO Pregnancy Category: A, ROUTE(S) : Vaginal

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