“Paricel 20” has been added to your cart. Checkout

Oseflu 75

Name: Oseflu 75
SKU: SKU-cV426q4o
Availability: InStock

Capsule - 75mg

Beximco Pharmaceuticals Ltd.

Generic: Oseltamivir

1 Capsule

Tk. 150

Description

Medicine Overview of Oseflu 75mg Capsule

Introduction

Oseflu 75 is an antiviral medicine used to treat and prevent influenza (flu) as well as, swine flu (H1N1 virus). It helps to relieve the symptoms of the flu virus infection like a stuffy or runny nose, sore throat, cough, body aches, tiredness, headache, fever, and chills.

Oseflu 75 prevents the flu virus from spreading inside the body. Influenza, commonly known as flu is an infection caused by a virus. This medicine should be taken only when prescribed by a doctor. It should be used in the dose and duration as advised by your doctor. It can be taken with or without food, although taking it with food can reduce the chance of feeling or being sick (nausea or vomiting).

Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medication too early may result in a relapse of the infection or failure to protect you from the flu.

Some common side effects include nausea, vomiting, stomach pain, and diarrhea. These side effects mostly occur after the first dose of the medicine and will usually stop as treatment continues. Please consult your doctor if these side effects persist for a longer duration.

Before taking it, tell your doctor if you have problems with your heart, liver or kidneys. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine.

Uses of Oseflu 75

Influenza (flu)

Side effects of Oseflu 75

Common

Nausea
Vomiting
Abdominal pain
Diarrhea

How to use Oseflu 75

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Oseflu 75 may be taken with or without food, but it is better to take it at a fixed time.

How Oseflu 75 works

Oseflu 75 is a neuraminidase inhibitor. It inhibits neuraminidase (influenza virus enzyme) that helps the viruses to enter into uninfected cells of the body to cause or spread influenza infection in the body. This is how it works against the virus to treat influenza (flu).

What if you forget to take Oseflu 75?

If you miss a dose of Oseflu 75, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

Oseflu 75 helps in the treatment and prevention of flu.

Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the symptoms of flu to come back.

Take it as soon as possible, ideally within two days of starting of flu symptoms.

Take it with food to avoid stomach upset.

It is not a substitute for flu vaccination. You might be prescribed both by your doctor.

Inform your doctor if you notice any changes in mood or behaviour, especially in children and adolescents.

Brief Description

Indication

Influenza

Administration

May be taken with or without food. May be taken w/ meals to reduce GI discomfort. Cap may be opened & mixed w/ sweetened food products eg chocolate syr, sweetened condensed milk, apple sauce or yogurt. Swallow mixture immediately after preparation.

Adult Dose

Oral
Treatment of Influenza A and B
Adult: 75 mg bid for 5 days. Initiate w/in 2 days of onset of symptoms.

Prophylaxis of influenza A and B
Adult: 75 mg once daily for at least 10 days. Initiate w/in 2 days of exposure. For community outbreak: May continue dosing for up to 6 wk.

Child Dose

Influenza A and B Treatment
<2 weeks: Safety and efficacy not established for treatment

Aged 2 weeks to <1 year
3 mg/kg PO BID x5 days

>1 year
<15 kg: 30 mg PO q12hr x5 days
15-23 kg: 45 mg PO q12hr x5 days
23-40 kg: 60 mg PO q12hr x5 days
>40 kg: 75 mg PO q12hr x5 days
Dosing considerations
Start within 24-48 hours of symptom onset

Influenza A and B Prophylaxis
<1 year: Safety and efficacy not established for prophylaxis

?1 year
<15 kg: 30 mg PO qDay x10 days
15-23 kg: 45 mg PO qDay x10 days
23-40 kg: 60 mg PO qDay x10 days
>40 kg: 75 mg PO qDay x10 days
Dosing considerations
Start within 2 days of exposure

Renal Dose

Renal impairment: Haemodialysis patient: 30 mg after each dialysis session. Peritoneal dialysis patient: 30 mg as a single dose.
CrCl (ml/min) Dosage Recommendation
<10 Not recommended.
>10-30 30 mg once daily.
>30-60 30 mg bid.

Contraindication

Hypersensitivity. Severe renal impairment.

Mode of Action

Oseltamivir is a prodrug of oseltamivir carboxylate (OC). OC is a potent selective competitive inhibitor of neuraminidase (an enzyme required for viral replication) of the influenza virus A and B. It prevents the release of viruses from infected host cell.

Precaution

Patient w/ resp disease, chronic cardiac disease. Renal and severe hepatic impairment. Immunocompromised patient. Childn. Pregnancy and lactation. Monitoring Parameters Monitor closely for signs and symptoms of behavioural changes.

Lactation: Unknown; use caution

Side Effect

1-10%
Abdominal pain,Conjunctivitis,Ear disorder,Epistaxis,Insomnia,Nausea,Vomiting,Vertigo

<1%
Aggravation of diabetes,Anemia,Arrhythmia,Confusion,Delirium,Hemorrhagic colitis,Hepatitis,Humerus fracture,Peritonsillar abscess,Pneumonia,Pseudomembranous colitis,Pyrexia,Rash,Seizure,Transaminases increased,Toxic epidermal necrolysis,Unstable angina,Swelling of face or tongue

Potentially Fatal: Anaphylaxis, severe dermatologic reactions.

Interaction

May potentially inhibit replication of influenza virus in live/attenuated influenza virus vaccine.