Oxecone M Chewable

Indication
Peptic ulcers, GERD, Heartburn, Gastritis
Administration
Take between meals & at bedtime.

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Adult Dose
Heartburn, Sour Stomach, & Acid Indigestion 5-10 mL (1-2 teaspoonfuls; 540-1080 mg) between meals and at bed time. not to exceed 80 mL (16 teaspoonfuls) in 24-hour period PO: 1-3 tablets between meals and at bed time.

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Child Dose
Safety & efficacy not established

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Contraindication
Magaldrate is contraindicated in patients with known hypersensitivity to magnesium and aluminium. It is also contraindicated in patients with impaired renal functions.
Mode of Action
Magaldrate is a hydroxymagnesium aluminate complex that is rapidly converted in gastric acid to magnesium and aluminium hydroxide, which is poorly absorbed and provides a sustained antacid effect with balanced efects on intestinal motility; increases lower esophageal sphincter tone and inhibits smooth muscle contraction and gastric emptying.
Precaution
Care should be taken in decreased kidney function, hypophosphataemia and weak people. Lactation: not known whether excreted in breast milk, use caution

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Side Effect
>10% Aluminum oxide Chalky taste,Constipation,Fecal impaction,Stomach cramps Frequency Not Defined Aluminum oxide Nausea,Vomiting,Aluminum intoxication,Hypophosphatemia,Osteomalacia, Magnesium oxide Diarrhea,Hypermagnesemia

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Interaction
Magaldrate may negatively influence drugs like tetracyclines, benzodiazepines, and indomethacin. High doses or prolonged usage may lead to an increment of defecation and a reduction in feces consistence. In some cases it can alter the functionality of the gastrointestinal tract, occasionally provoking constipation or diarrhea.