Pedilid 150

Introduction
Pedilid 150 is an antibiotic used to treat various types of bacterial infections. It is effective in resolving most infections of the respiratory tract, ear, nose, throat, lungs and skin. It stops the growth of infection causing bacteria and thus resolves the symptoms. Pedilid 150 should be taken orally on an empty stomach. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. Commonly seen side effects seen with this medicine include nausea, vomiting, pain in the abdomen and diarrhea. These are usually temporary and subside with the completion of treatment. Consult your doctor if these side effects do not resolve or persist for a longer duration. Inform your doctor if you have any previous history of allergy or heart problems before taking this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.

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Uses of Pedilid 150
Bacterial infections
Side effects of Pedilid 150
Common
Nausea
Vomiting
Abdominal pain
Diarrhea
Allergy
How to use Pedilid 150
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pedilid 150 is to be taken empty stomach.
How Pedilid 150 works
Pedilid 150 is an antibiotic. It works by preventing synthesis of essential proteins required by bacteria to carry out vital functions. Thus, it stops the bacteria from growing, and prevents the infection from spreading.
What if you forget to take Pedilid 150?
If you miss a dose of Pedilid 150, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Your doctor has prescribed Pedilid 150 to cure your infection and improve your symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
Take it 1 hour before or two hours after food.
Do not take antacids 2 hours before or after taking Pedilid 150.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn’t stop or if you find blood in your stools.
Stop taking Pedilid 150 and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Brief Description
Indication
Pneumonia, Pharyngitis, Susceptible infections, Sinusitis, Otitis media, Cellulitis,Tonsillitis, Folliculitis, Carbuncles, Prostatitis, Urethritis, Acute and chronic bronchitis, Bronchopneumonia, Furuncles, Pyoderma, Impetigo and infected dermatitis, Cervicitis and salpingitis
Administration
Should be taken on an empty stomach. Take at least 15 min before meals.
Adult Dose
Oral Susceptible infections Adult: 150 mg bid or 300 mg once daily for 5-10 days in susceptible infections. Hepatic impairment: Usual daily doses should be halved in hepatic impairment.

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Child Dose
Oral Susceptible infections Child: 6-40 kg: 5-8 mg/kg daily.

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Renal Dose
Renal impairment: Dosage adjustment may be required.
Contraindication
Hypersensitivity. Porphyria.
Mode of Action
Roxithromycin inhibits protein synthesis by irreversibly binding to the 50s ribosomal subunits thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting in stunted cell growth.
Precaution
Hepatic impairment. Monitor liver function. Prolonged treatment increases risk of hepatotoxicity. History of arrhythmias.
Side Effect
Nausea, vomiting, abdominal pain, diarrhoea, weakness, malaise, anorexia, constipation, dyspepsia, flatulence; hepatitis; rashes, headache, dizziness, weakness, changes in blood counts; increased liver enzyme values; eosinophilia; rarely, acute pancreatitis.
Interaction
May raise serum levels of ciclosporin and digoxin. Increased risk of rhabdomyolysis when used with simvastatin.