Medicine Overview of Tenoren Plus 50mg+25mg Tablet
Tenoren Plus is a medicine used to treat hypertension (high blood pressure). Tenoren Plus is a combination of two medicines that helps to control blood pressure when a single medication is not effective. It helps to reduce chances of any future heart attack and stroke.
Tenoren Plus is taken with or without food, preferably in the morning to avoid frequent urination at night. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.
Nausea, headache, and fatigue are some common side effects of this medicine. Consult your doctor If any of these bother you, or get worse, or do not go away. Drink plenty of fluids while taking medicine to overcome muscle weakness, dry mouth, and extreme thirst. Dizziness or headache may occur due to low blood pressure but this gets better with time.
Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions. You should have your blood pressure, kidney function, blood sugar level and the levels of salts such as potassium or magnesium checked regularly to make sure that this medicine is working properly.
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- Hypertension (high blood pressure)
- Nausea
- Diarrhea
- Headache
- Fatigue
- Dizziness
- Cold extremities
- Increased blood uric acid
- Decreased potassium level in blood
- Glucose intolerance
- Slow heart rate
- Decreased sodium level in blood
- Decreased magnesium level in blood
- Increased calcium level in blood
- Increased blood lipid level
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It is a combination of two blood pressure lowering medications used for the treatment of high blood pressure.
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It can be taken with or without food.
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Do not stop taking Tenoren Plus suddenly as it can cause your blood pressure to rise suddenly thereby increasing the risk of heart attack and stroke.
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It may cause dizziness. If this happens to you, get up slowly when rising from a sitting or lying position.
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It can hide symptoms of low blood sugar if you’re diabetic. Monitor your blood sugar levels regularly.
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Tenoren Plus may cause dehydration. Drink plenty of fluids and Inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth.
Adult: Per tab contains Atenolol (mg)/Chlorthalidone (mg): 50/25 or 100/25. Initially one tab of 50/25 once daily; may increase to one tab of 100/25 based on response.
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Bronchospastic disease, renal or hepatic impairment, elderly. May aggravate peripheral arterial circulatory disorder. Beta-blocker can depress myocardial contractility; continued use in patients without history of cardiac failure may in some cases, lead to cardiac failure. Caution in patients receiving anaesthetic agents that may depress myocardium. In patients with coronary artery disease, abrupt withdrawal may cause angina pectoris exacerbation, MI. Atenolol may mask signs (tachycardia) of hypoglycaemia and thyrotoxicosis. Latent DM may manifest with Chlorthalidone therapy.
Chlorthalidone can cause hyperuricaemia and precipitate gout. Monitor renal functions, potassium levels, and signs of fluid and electrolytes imbalance. Discontinue if progressive renal impairment is evident. Not recommended in pregnancy and lactation. Safety and efficacy in paediatric patients have not been established.
Lactation: excreted in breast milk, use caution
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Renal impairment:
CrCl (ml/min)
15-35 Max dose of Atenolol component: 50 mg/day
<15 Max dose of Atenolol component: 50 mg every other day.
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Atenolol: Dyspnoea, wheeziness, bradycardia, hypotension, cold extremities, fatigue, dizziness, insomnia, lethargy, confusion, headache, depression, nightmares, nausea, diarrhoea, constipation, impotence, paraesthesia, rash, Raynaud’s phenomenon.
Chlorthalidone: Orthostatic hypotension, GI disturbances, jaundice, pancreatitis, vertigo, lethargy, paraesthesia, photosensitivity, rash, muscle cramps, hypokalaemia, hyponatraemia, hyperglycaemia, hyperuricaemia or gout, leucopenia, agranulocytosis, aplastic anaemia, thrombocytopenia.
Potentially Fatal: Atenolol: Heart failure, 2nd or 3rd degree AV block. Chlorthalidone: Hypersensitivity reaction including toxic epidermal necrolysis.
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