Uriten

Introduction
Uriten is an alpha adrenergic antagonist that is used in the treatment of benign prostatic hyperplasia. It helps to relieve symptoms like difficulty in passing urine. However, it does not decrease the size of the prostate. Uriten is advised to take it in a dose and duration as per prescription. It should be taken with food, but take at the same time regularly. Swallow the medicine as a whole without crushing or chewing it. You should not stop taking the medicine without consulting the doctor as it may lead to the worsening of your symptoms. The course of the treatment should be completed for better efficacy of the medicine. Some common side effects of this medicine are upper respiratory tract infection, headache, and tiredness. It may also lead to blurry vision or dizziness, so it is advised to avoid driving while on the medication. If any of the side effects persist or bother you, you must consult the doctor without delay. Simple lifestyle changes can help you manage your symptoms better. Try to urinate as soon as you feel the urge, however, never strain or push to empty your bladder. You should avoid drinking caffeinated or alcoholic drinks at night and a few hours before going to bed or going out. Before receiving the treatment, inform your doctor if you are on any medication for any other health condition. If you are pregnant or breastfeeding, tell your doctor prior to the treatment. If you have to undergo eye surgery due to cataract or glaucoma than inform your eye doctor about the usage of this medicine. Patients with liver or kidney disease must be cautious while receiving the prescription, and they must receive regular follow-ups as per the doctor’s advice.

_
Uses of Uriten
Benign prostatic hyperplasia
Side effects of Uriten
Common
Dizziness
Headache
Tiredness
How to use Uriten
Use it as advised by your doctor or check the label for directions before use. Uriten is to be taken with food.
How Uriten works
Uriten is an alpha blocker. It works by relaxing muscle around the bladder exit and prostate gland so urine is passed more easily.
What if you forget to take Uriten?
If you miss a dose of Uriten, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Flotral 10 Tablet PR helps in relieving the symptoms of enlarged prostate. It does not decrease the size of the prostate.
Flotral 10 Tablet PR must be taken with food.
You will feel better within hours or days of starting the treatment. Full effect is usually seen within 2 weeks.
Flotral 10 Tablet PR may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
If you are scheduled to undergo an eye surgery due to cataract or glaucoma, inform your eye doctor about the usage of Flotral 10 Tablet PR.
Inform your doctor if you have ever been diagnosed with kidney or liver problems.
Brief Description
Indication
Oral Benign prostatic hyperplasia Adult: 2.5 mg tid. Max: 10 mg/day. 1st dose should be given before bedtime. Extended-release: 10 mg once daily. Elderly: Initially, 2.5 mg bid. Acute urinary retention: Extended-release: 10 mg once daily to be taken from 1st day of catheterisation. Duration: 3-4 days. Hepatic impairment: Mild to moderate: Initially, 2.5 mg daily, may increase to 2.5 mg bid according to response. Severe: Contraindicated.

_
Administration
Additive effect on QT interval prolongation when used w/ QT-prolonging drugs. Concomitant admin w/ other ?1-adrenergic blocking agents, atenolol or diltiazem may result in additive CV effects. Increased plasma alfuzosin concentrations w/ cimetidine. Potentially Fatal: Concurrent use w/ potent CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, ritonavir) increase plasma alfuzosin levels.

_
Adult Dose
Elderly; hypertension; coronary insufficiency; angina (discontinue); renal or hepatic impairment. Monitor BP regularly. May affect ability to drive or operate machinery.
Renal Dose
Alfuzosin is a quinazoline derivative which exhibits selectivity for alpha1-adrenergic receptors in the lower urinary tract. Blockade of these adrenoreceptors causes relaxation of smooth muscle in the bladder neck and prostate, resulting in improvement in urine flow and a reduction in symptoms of benign prostatic hyperplasia (BPH).
Mode of Action
Administration Should be taken with food. Swallow whole. Extended-Release: Should be taken with food. Take immediately after the same meal each day. Swallow whole, do not chew/crush.

_
Precaution
Benign prostatic hyperplasia (BPH)
Side Effect
Renal Impairment Initially, 2.5 mg bid. Adjust dose according to response.
Pregnancy Category Note
1-10% Abdominal pain (1-2%),Back pain (1-2%),Brochitis (1-2%),Constipation (1-2%),Dizziness (5.7%),Dyspepsia (1-2%),Fatigue (2.7%),Headache (3%),Impotence (1-2%),Nausea (1-2%),Pharyngitis (1-2%),URT infection (3%),Sinusitis (1-2%),Upper respiratory infection (3%)

_
Interaction
Severe hepatic impairment; history of postural hypotension and micturition syncope; intestinal occlusion; severe renal insufficiency; lactation.