Medicine Overview of V-Nil 25mg+50mg Tablet
V-Nil is a combination medicine used in the treatment of vertigo and motion sickness. It prevents the feeling of nausea, vomiting, light-headedness and other symptoms of vertigo.
V-Nil is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
Common side effects of this medicine include dryness in the mouth, headache, and fatigue. These are usually mild and disappear after a short time. Consult your doctor if they persist. This medicine can also cause dizziness and drowsiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your drowsiness.
- Vertigo
- Motion sickness
- Dryness in mouth
- Allergic reaction
- Drowsiness
- Headache
- Fatigue
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V-Nil helps treat nausea and vomiting in pregnant women.
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Take it on an empty stomach with a glass of water.
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V-Nil may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you.
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Do not take V-Nil with other sedating medications such as those for cough and cold as the combination could worsen dizziness leading to falls or other accidents.
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Do not take V-Nil while breastfeeding.
Oral
Motion sickness
Adult: 25-50 mg Meclizine 1 hr before travelling and repeat 24 hrly if needed.
Vertigo and vestibular disorders
Adult: 25-100 mg Meclizine daily in divided doses. Discontinue if there is no response after 1-2 wk of treatment.
Radiation sickness:
50 mg Meclizine administered 2-12 hours prior to radiation treatment.
Pyridoxine (vitamin B6) has been shown to be safe and effective in dosages of 50 to 200 mg per day.
Oral
<12 years: Safety and efficacy not established
Meclozine blocks vasopressor response to histamine and has a slight blocking action against acetylcholine. It decreases excitability of the middle ear labyrinth and blocks conduction in the middle ear vestibular-cerebellar pathways.
Pyridoxine is a water-soluble vitamin which functions in the metabolism of carbohydrates, proteins and fats. It is essential in Hb formation and GABA synthesis within the CNS. It also aids in the release of glycogen stored in the liver and muscles.
Prostate hypertrophy, obstruction of bladder neck, narrow angle glaucoma, pyloric stenosis. May impair ability to drive or operate machinery. Pregnancy.
Lactation: Not known if excreted in milk; use caution

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