Medicine Overview of Valcap 160mg Capsule
Valcap is a medicine used to treat high blood pressure and heart disease. Lowering blood pressure helps to prevent future heart attack and stroke. This medicine is also effective in preserving kidney function in patients with diabetes.
Valcap can be prescribed either alone or in combination with other medicines. It may be taken with or without food during the day or at night. However, try to take it at the same time each day to get the most benefit. It is important to continue taking it regularly even if you feel well or if your blood pressure is controlled. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. This is a widely used medicine and is considered safe for long-term use.
Making some changes in your lifestyle will also help lower your blood pressure. These may include regular exercise, losing weight, smoking cessation, reducing alcohol intake, and reducing the amount of salt in your diet as advised by your doctor. This medicine is tolerated well by most patients and has few side effects. Dizziness, particularly after the first dose, is known to occur in some people. This may be associated with headache. Let your doctor know if these side effects bother you or do not go away. No weight gain has been seen with the regular use of this medicine.
Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding mothers should also consult their doctor before taking it. Your doctor may check your kidney function, blood pressure and potassium levels in your blood at regular intervals while you are taking this medicine.
- Hypertension (high blood pressure)
- Heart failure
- Prevention of heart attack and stroke
- Headache
- Dizziness
- Flu-like symptoms
- Stomach pain
- Decreased blood pressure
- Diarrhea
- Back pain
- Rash
- Increased creatinine level in blood
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It can make you feel dizzy for the first few days. Rise slowly if you have been sitting or lying down for a long time.
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Your doctor may get regular tests done to monitor the level of urea, creatinine, and potassium in your blood.
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Avoid taking anti-inflammatory medicines such as ibuprofen along with this medicine without consulting your doctor.
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Do not take Valcap if you are pregnant or breastfeeding.
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Do not stop taking it suddenly without talking to your doctor.
Oral
Hypertension
Adult: Initially, 80 mg once daily, may be increased to 160 mg once daily if needed. Max: 320 mg once daily.
Heart failure
Adult: Initially, 40 mg bid, may be increased to 160 mg bid if tolerated.
Post myocardial infarction
Adult: Start as early as 12 hr after MI in stable patients at an initial dose of 20 mg bid, doubled at intervals over a few wk up to 160 mg bid if tolerated.
Elderly: No dosage adjustment needed.
Hepatic impairment: Mild to moderate: Max: 80 mg once daily. Severe: Contraindicated.
Oral
Hypertension
Child: As tab: >6 yr <35 kg: Initially, 40 mg once daily. Max: 80 mg once daily;
35-80 kg: Initially, 80 mg once daily. Max: 160 mg once daily;
>80 kg: Initially, 80 mg once daily. Max: 320 mg once daily.
Renal impairment
CrCl >30 mL/min: No dose adjustment necessary in adults
CrCl <30 mL/min: Use with caution in adults; not studied in children
>10%
Dizziness (17%; heart failure),Increased blood urea nitrogen (BUN; 17%)
1-10%
Hyperkalemia (4-10%),Dizziness (2-8%; hypertension),Hypotension (1-7%; heart failure),Fatigue (3%),Viral infection (3%),Neutropenia (2%),Syncope (>1%),Upper abdominal pain (>1%),Vertigo (>1%)
Frequency Not Defined
Headache,Cough (rare)
Potentially Fatal: Blood dyscrasias (e.g. neutropenia).
May antagonise hypotensive effects and increase the risk of renal impairment w/ NSAIDs. Increased risk of hyperkalaemia w/ K-sparing diuretics, K supplements or K-containing salt substitutes.
Potentially Fatal: Increased risk of hypotension, hyperkalemia and changes in renal function (including acute renal failure) when used w/ aliskiren in patients w/ diabetes and renal impairment (GFR <60 mL/min).
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