Vitabest

Indication
Vitamin B deficiency, Skin & nervous system, intense physical activity, optic neuritis, peripheral neuritis

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Adult Dose
Oral Adults: 10 ml (2 teaspoonful) twice daily

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Child Dose
Oral Children: 1 teaspoonful (5 ml) syrup twice times a day.

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Contraindication
Contraindicated in patients hypersensitive to any of its components.
Mode of Action
Vitamin B: Plays a role in the synthesis and maintenance of coenzyme A. Necessary for lipid metabolism, carbohydrate metabolism, tissue respiration, glycogenolysis, inhibition of very low-density lipoprotein (VLDL) synthesis. May increaase chylomicron triglyceride removal from plasma. Pyridoxine is a water-soluble vitamin which functions in the metabolism of carbohydrates, proteins and fats. It is essential in Hb formation and GABA synthesis within the CNS. It also aids in the release of glycogen stored in the liver and muscles. Riboflavin (vitamin B2) is required for energy utilisation from food. It is essential for normal tissue respiration. It is also necessary for the activation of pyridoxine and conversion of tryptophan to nicotinic acid. Thiamine forms thiamine pyrophosphate by combining with adenosine triphosphate; essential coenzyme in carbohydrate metabolism. Niacin, like the other B vitamins, is necessary for energy production (NAD). It is important in the synthesis of DNA, fatty acids and cholesterol. It is also important in brain function. Niacin is found in brewer’s yeast, liver, poultry, peanuts, fish, whole grains, eggs and milk. The nicotinic acid form may dilate blood vessels and cause a “flush.”

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Side Effect
Generally well tolerated.
Interaction
Pyridoxine: Isoniazid, penicillamine and oral contraceptives may result in greater requirement in pyridoxine dose. Reduces the effects of levodopa, phenobarbitone, altretamine and phenytoin. Riboflavin: Rate and extent of absorption may be affected by propantheline bromide.

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