“Gavilac” has been added to your cart. Checkout

Afix 200 (Capsule)

Name: Afix 200 (Capsule)
SKU: SKU-eQ4jVMbh
Availability: InStock

Capsule - 200mg

Aristopharma Limited

Generic: Cefixime

7 Capsules (1 Strip)

Original price was: Tk. 315.Current price is: Tk. 280.

Description

Medicine Overview of Afix 200 (Capsule) 200mg capsule

Introduction

Afix 200 (Capsule) is an antibiotic belonging to the cephalosporin group, which is used to treat a variety of bacterial infections. It is effective in infections of the respiratory tract (eg. pneumonia), urinary tract, ear, nasal sinus, throat, and some sexually transmitted diseases. Afix 200 (Capsule) may be taken on an empty stomach or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose will depend on what you are being treated for, but

Uses of Afix 200 (Capsule) Tablet

Bacterial infections

Side effects of Afix 200 (Capsule) Tablet

Common

Nausea
Stomach pain
Indigestion
Diarrhea

How to use Afix 200 (Capsule) Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Afix 200 (Capsule) may be taken with or without food, but it is better to take it at a fixed time.

How Afix 200 (Capsule) Tablet works

Afix 200 (Capsule) is an antibiotic. It kills the bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

What if you forget to take Afix 200 (Capsule) Tablet?

If you miss a dose of Afix 200 (Capsule), take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

Your doctor has prescribed Afix 200 (Capsule) to cure your infection and improve your symptoms.

Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection harder to treat.

Take it with food to avoid an upset stomach.

Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.

Avoid consuming alcohol while taking Afix 200 (Capsule) as it may cause increased side effects.

Discontinue Afix 200 (Capsule) and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

Brief Description

Indication

Pneumonia, Pharyngitis, Typhoid fever, Susceptible infections , Sinusitis, Otitis media, Tonsillitis, Soft tissue infections, Respiratory tract infections, Acute Exacerbations of Chronic bronchitis, Gonococcal urethritis, Acute bronchitis

Administration

May be taken with or without food. May be taken w/ food or milk to reduce GI discomfort.

Adult Dose

Acute Bronchitis & Acute Exacerbations of Chronic Bronchitis, Otitis Media, Pharyngitis/Tonsillitis, Uncomplicated Urinary Tract Infections
Adult: 200 or 400 mg daily as a single dose or in two divided doses

Gonorrhea: 400 mg as a single dose.
Typhoid fever: 20 mg/kg body weight daily in two divided dose.
The usual treatment of is 7 days.
This may be continued for up to 14 days according to the severity of infection.

Child Dose

Child: PO 8 mg/kg/day if <50 kg q12–24h
For convalescent oral therapy of serious infections, up to 20 mg/kg/day

Child over 12 years:
Capsule: 200 or 400 mg daily as a single dose or in two divided doses

Powder for Suspension & DS Powder for Suspension & Paediatric Drops:

Children above 6 months: 8 mg/kg daily in 1-2 divided doses or
6 months-1year: 75 mg daily
1-4 years: 100 mg daily
5-10 years: 200 mg daily

Typhoid Fever
15-20 mg/kg/day PO divided q12hr for 7-14 days; not to exceed 400 mg/day

<6 months: Safety and efficacy not established

Renal Dose

Renal impairment: Dose reduction is necessary.
CrCl (ml/min)
<20 Max: 200 mg daily.

Contraindication

Hypersensitivity to cephalosporin.

Mode of Action

Cefixime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.

Precaution

History of allergy to penicillins; pregnancy, lactation; renal failure; GI disease.

Lactation: Unknown whether drug is excreted in milk

Side Effect

>10%
Diarrhea (16%)

Frequency Not Defined
Abdominal pain,Candidiasis,Dizziness,Dyspepsia,Elevated transaminases,Eosinophilia,Erythema multiforme,Fever,Flatulence,Headache,Increased blood urea nitrogen (BUN),Increased creatinine,Leukopenia,Nausea,Prolonged prothrombin time (PT),Pruritus,Pseudomembranous colitis,Rash,Serum sickness-like reaction,Stevens-Johnson syndrome,Thrombocytopenia,Urticaria,Vaginitis,Vomiting

Potentially Fatal: Pseudomembranous colitis.

Pregnancy Category Note

Pregnancy Available data from published observational studies, case series, and case reports over several decades with cephalosporin use, including cefixime, in pregnant women have not established drug-associated risks of major birth defects, miscarriage, or adverse maternal or fetal outcomes Maternal gonorrhea may be associated with preterm birth, low neonatal birth weight, chorioamnionitis, intrauterine growth restriction, small for gestational age and premature rupture of membranes; perinatal transmission of gonorrhea to offspring can result in infant blindness, joint infections, and bloodstream infections Lactation There are no available data on presence of drug in human milk, effects on breastfed infant, or on milk

Interaction

Increased concentrations with probenecid.

Potentially Fatal: May increase prothrombin time with anticoagulants.