Medicine Overview of Aristocort 40mg/ml Injection
Aristocort is a steroid. It is used for treatment of wide variety of medical conditions such as allergic disorders, severe allergic reactions, and rheumatic disorders. It provides relief by preventing the release of substances that cause inflammation and by suppressing the immune system.
Aristocort is given by a doctor or a healthcare professional. You should not self-administer this medicine at home. Using the medicine regularly at the right times increases its effectiveness. It is important to keep using the medicine regularly until your doctor tells you it is safe to stop.
Aristocort may cause few side effects such as infection, headache, joint pain, or injection site reaction. Talk to your doctor if you are worried about side effects or they do not go away. Using corticosteroids like may Aristocort make you more susceptible to viral infections, so you should stay away from people who have these infections. In general, you should try to avoid situations which make your symptoms worse (things like pollen and dust mites) and it is best not to smoke.
Before starting to use Aristocort you should let your doctor know if you are pregnant or breastfeeding, discuss the risks and benefits with your healthcare team. If you use this medicine for a long time, your doctor may want to carry out certain medical tests to check your progress.
- Allergic disorders
- Severe allergic reactions
- Rheumatic disorder
- Headache
- Infection
- Joint pain
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Side effects such as mood changes or stomach problems can happen when you start taking Aristocort. Inform your doctor if this bothers you.
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Do not stop taking Aristocort suddenly without talking to your doctor first as it may worsen your symptoms.
Dilute with local anesthetic (1% or 2% lidocaine without parabens) before intra-articular or intralesional injection
Dilute with D5/NS or D10/NS or NS or SWI before intralesional injection
Intramuscular
Suppression of allergic and inflammatory disorders
Adult: As acetonide: 20-80 mg via deep IM into gluteal muscles.
Symptomatic control for hay fever
Adult: As acetonide: 40-100 mg via deep IM into gluteal muscles.
Rheumatic or arthritic disorders
Adult: 60 mg IM every 6 weeks; may be supplemented by additional 20-100 mg IM PRN
Intra-articular
Inflammatory joint diseases
Adult: As acetonide: Smaller joints: 2.5-5 mg (up to 10 mg), larger joints: 5-15 mg (up to 40 mg).
Max: 20-80 mg/treatment.
Intradermal
Inflammatory skin conditions
Adult: As acetonide: 1-3 mg/site. Max: 30 mg in total if several sites of inj used. Max: 12.5 mg/inj site. Max: 25 mg/lesion.
Intramuscular
Suppression of allergic and inflammatory disorders
Child: As acetonide: deep IM into gluteal muscle: initial 0.11 to 1.6 mg/kg/day in 3-4 divided doses.
Do not use in premature infants and infants of low birth weight as it contains benzyl alcohol.
Child: 6-12 years: 0.03-0.2 mg/kg IM every 1-7 days
>12 years: 60 mg IM every 6 weeks; may be supplemented by additional 20-100 mg IM PRN
>12 years, intralesional injection (10 mg/mL suspension): 1 mg per injection site 1 or more times weekly; not to exceed 30 mg/day
Symptomatic control for hay fever
Child: As acetonide: deep IM into gluteal muscle: initial 0.11 to 1.6 mg/kg/day in 3-4 divided doses.
Do not use in premature infants and infants of low birth weight as it contains benzyl alcohol.
Diabetes; hypertension, renal and liver impairment; glaucoma; psychosis; delayed tissue healing; cirrhosis; heart failure; recent MI; hypothyroidism; osteoporosis; peptic ulceration; thromboembolic disorders. Monitor height in children on prolonged therapy. Avoid rapid drug withdrawal. Elderly, children, pregnancy, lactation.
Lactation: Excreted in breast milk; use caution
HPA axis supression, intracranial hypertension, Cushing’s syndrome, growth retardation in children; osteoporosis, fractures. Peptic ulceration; glaucoma; hyperglycaemia; GI upsets; increased appetite; increased fragility of skin; behavioural changes.
Potentially Fatal: Acute adrenal insufficiency may be precipitated by infection or trauma in patients on long-term corticosteroid therapy or rapid withdrawal.

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