Medicine Overview of Conart 1mg Tablet
Oral
Oedema
Adult: 1 mg once daily. Give 2nd dose 6-8 hr later if necessary.
Elderly: 0.5 mg daily.
Refractory oedema
Adult: Initially, 5 mg daily increased by 5 mg every 12-24 hr as required. High doses may be divided in 2-3 doses. Max: 10 mg/day.
Hypertension
Adult: 0.5-1 mg daily. Max: 5 mg/day.
Parenteral
Emergency cases of oedema
Adult: 0.5-1 mg via slow IV/IM inj, subsequently adjust dose according to response.
Intravenous
Pulmonary oedema
Adult: 1-2 mg IV repeated 20 min later if necessary, or 2-5 mg in 500 ml of a suitable infusion fluid given over 30-60 min.
Show less
Pregnancy, lactation; regular monitoring of serum electrolytes (especially potassium, calcium, magnesium); in case of hypokalemia, potassium supplements/potassium-sparing diuretics added. Monitor blood-glucose, BUN, creatinine levels as well as blood counts. Sulfonamide allergy. CHF patients on digitalis, K losing nephropathy, hepatic cirrhosis and ascitis, diarrhoeal states.
Lactation: Unknown whether drug is excreted in breast milk; use with caution
Show less
>10%
Hyperuricemia (18%),Hypochloremia (15%),Hypokalemia (15%),Azotemia (11%)
1-10%
Hyponatremia (9%),Hyperglycemia (7%),Increased serum creatinine (7%),Variations in phosphorus (5%),Variations in CO2 content (4%),Variations in bicarbonate (3%),Variations in calcium (2%),Dizziness (1%),Muscle cramps (1%),Ototoxicity (1%)
<1%
Asterixis,Dehydration,Hypotension,Orthostatic hypotension,Pruritus,Rash,Renal failure,Serious skin reactions (ie, Stevens-Johnson syndrome, toxic epidermal necrolysis),Vertigo,Vomiting
Potentially Fatal: Encephalopathy (in patients with preexisting liver disease).
Show less
Pregnancy category: C
Lactation: Unknown whether drug is excreted in breast milk; use with caution
Show less
Reduced diuretic and natriuretic actions by probenecid. Indometacin blunts action of bumetanide; concurrent usage with antihypertensives may increase risk of orthostatic hypotension.
Potentially Fatal: Avoid concurrent usage with ototoxic drugs such as aminoglycoides and nephrotoxic drugs. Reduced lithium excretion via kidneys.
Show less
Reviews
Clear filtersThere are no reviews yet.