Medicine Overview of Fusidic Plus 2%+1% Ointment
Topical/Cutaneous
Mild to moderately severe atopic dermatitis with secondary bacterial infections
Adult: As cream/ointment containing hydrocortisone 1% and fusidic acid 2%: Apply to affected area(s) bid until there is improvement.
Usual treatment duration: 2 wk.
Topical/Cutaneous
Mild to moderately severe atopic dermatitis with secondary bacterial infections
Child: >3 yr: As cream/ointment containing hydrocortisone 1% and fusidic acid 2%: Apply to affected area(s) bid until there is improvement.
Usual treatment duration: 2 wk.
Not to be used in or near the eye(s) as it may cause conjunctival irritation; may also increase the risk of increased intraocular pressure, glaucoma and cataract. Sufficient dermal absorption may occur under occlusive dressing leading to adrenal suppression and other systemic effects. May mask hypersensitivity reactions. Not to be used for >14 days in the absence of any clinical improvement. Pregnancy and lactation.
Fusidic Acid: Synergistic action with antistaphylococcal penicillin. Antagonism with ciprofloxacin.
Hydrocortisone : Clearance may be increased by hepatic enzyme inducers eg phenobarb, phenytoin & rifampin. Metabolism may be inhibited by troleandomycin & ketoconazole. May increase clearance of chronic high dose aspirin. Risk of enhanced or diminished effects of anticoagulant.
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