G-hypophos

Indication
Hyperphosphatemia
Administration
Should be taken with food.
Contraindication
Patients with hypercalcaemia.
Mode of Action
Sequesters phosphate in the intestine by forming insoluble phosphates that are excreted faecally, thus reducing serum phosphate conc & secondary hyperparathyroidism.

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Precaution
Patients undergoing chronic hemodialysis. Renal impairment, diseases associated with hypercalcaemia such as sarcoidosis & some malignancies. Avoid in patients with calcium renal calculi or a history of renal calculi. Maintenance of normal serum calcium levels is important for maternal and fetal well being; hypercalcemia during pregnancy may increase risk for maternal and neonatal complications(eg, stillbirth, preterm delivery, neonatal hypocalcemia and hypoparathyroidism);calcium acetate treatment, as recommended, is not expected to harm a fetus if maternal calcium levels are properly monitored during and following treatment Lactation: unknown

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Side Effect
Arrhythmias,Hypomagnesemia,Hypophosphatemia,Hypotension,Nausea,Pruritus (rare),Weakness Hypercalcemia,Anorexia,Coma,Confusion,Delirium,Headache,Nausea,Vomiting

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Pregnancy Category Note
Pregnancy Category: C Maintenance of normal serum calcium levels is important for maternal and fetal well being; hypercalcemia during pregnancy may increase risk for maternal and neonatal complications(eg, stillbirth, preterm delivery, neonatal hypocalcemia and hypoparathyroidism);calcium acetate treatment, as recommended, is not expected to harm a fetus if maternal calcium levels are properly monitored during and following treatment Lactation: unknown

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Interaction
Tetracycline antibiotics, thiazide diuretics, vit D, corticosteroids, bisphosphonates, fluoride, some fluoroquinolones.