Medicine Overview of Osmosol 20% IV 20% Infusion
Osmosol 20% IV is a medicine used in the treatment of acute renal (kidney) failure, cerebral edema (accumulation of excessive fluid in the brain) and to reduce the pressure inside the eyes in a condition called glaucoma.
Osmosol 20% IV works by removing excess water and also relieves inflammation in the affected areas. It may be used alone or in combination with other medicines. It is administered as an injection under the supervision of a medical professional and should not be self administered. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember.
Some common side effects of this medicine include nausea, vomiting, headache, and dehydration. You may also notice some injection site reactions such as pain, redness or swelling. However, these are temporary and usually subside on their own after some time. Please consult your doctor if these do not subside or bother you. Regular monitoring by blood tests may be required while using this medicine.
- Acute renal failure
- Cerebral edema (accumulation of excessive fluid in the brain)
- Glaucoma
- Nausea
- Vomiting
- Headache
- Dehydration
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It is given as an injection into the veins by a doctor or healthcare professional.
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Your doctor may get regular blood tests done to monitor sodium and potassium level, kidney function, and lung function while you are taking this medicine.
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Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Intravenous
Oliguric phase of renal failure
Adult: 50-100 g in a 24-hr period by IV infusion. Adjust rate of administration to maintain a urine flow of at least 30-50 mL/hr.
Cerebral oedema, Reduction of raised intraocular pressure
Adult: 0.25-2 g/kg by IV infusion given over 30-60 minutes.
Renal function testing
Adult: 0.2 g/kg infused over 3-5 min.
Intravenous
Edema
0.25-1 g/kg IV initially; maintenance dose of 0.25-0.5 g/kg IV q4-6hr
Anuria/Oliguria
Test dose: 0.2 g/kg IV over 3-5 minutes; not to exceed 12.5 g
Discontinue if no diuresis within 2 hr
Hypervolaemia; urinary tract obstruction; check for signs of fluid and electrolyte imbalance. Should not be administered with whole blood. Pregnancy, lactation.

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