Oxizol

Introduction
Oxizol is an antifungal medicine used to treat fungal infections of the skin. It works by killing the fungus that causes infections such as athlete’s foot, Dhobie Itch, thrush, ringworm and dry, flaky skin. Oxizol should be used in the dose and duration as prescribed by your doctor. This medicine should be used regularly to get the most benefit from it. Do not use more than you need, it will not clear your condition faster and may only increase the side effects. Skin infections will usually get better after 2 to 4 weeks. Do not use the cream for longer than your doctor has told you to and let him or her know if your condition does not improve after 2 to 4 weeks of treatment. The effects of medicine can be increased by keeping the affected area clean and dry, and washing hands before and after treating the infection. If you have athlete’s foot, wash your socks or tights thoroughly and change your shoes daily if possible. The most common side effects of using this cream include a burning sensation and irritation, dryness, peeling or blistering of the skin. Occasionally it can cause thinning of your hair. These are not usually serious, but you should call your doctor if you think you might have a severe allergic reaction. Signs of this include rash, swelling of the lips, throat or face, swallowing or breathing problems, feeling dizzy or faint and nausea. Get emergency help if this happens. Avoid direct contact of the medicine with your eyes. In case of direct contact, wash your eyes with water and seek immediate medical attention. It is not likely that other medicines you take by mouth or injection will affect the way this medicine works, but talk to your doctor before using it if you have recently used another medicine that contains a steroid or had an allergic reaction to another antifungal medicine. This medicine should only be used if it is clearly needed if you are pregnant or breastfeeding. Ask your doctor if it is safe.

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Uses of Oxizol
Fungal skin infections
Side effects of Oxizol
Common
Application site reactions (burning, irritation, itching and redness)
How to use Oxizol
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
How Oxizol works
Oxizol is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection.
What if you forget to take Oxizol?
If you miss a dose of Oxizol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Oxizol helps treat skin infections caused by many different types of fungi.
Some tips for personal hygiene:
Finish the full course of treatment even if you feel better.
It can take a few weeks for the infection to clear and a few months before the skin returns to its normal color.
It is not taken orally, so it does not cause many side effects.
Apply an amount sufficient to cover the affected area and 1 inch of the immediate surrounding skin.
Avoid getting it in the eyes, nose, or mouth. If accidental exposure occurs, rinse immediately with plenty of water.
Inform your doctor if the infection has not cleared up after four weeks of treatment.
Brief Description
Indication
Tinea pedis, Tinea cruris, Tinea corporis, Pityriasis versicolor
Adult Dose
Topical/Cutaneous Tinea cruris; Tinea corporis; Tinea pedis Adult: Apply 1% cream once or bid. Duration of treatment: 2 wk for tinea corporis and tinea cruris or 1 mth for tinea pedis. Pityriasis versicolor Adult: As 1% cream: Apply to affected areas once daily for 2 wk.

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Contraindication
Hypersensitivity.
Mode of Action
Oxiconazole, a synthetic azole antifungal, is usually fungistatic but may be fungicidal in high concentrations. It exerts its antifungal activity by interfering w/ ergosterol synthesis and altering cellular membranes. It also has some antibacterial activity against aerobic gm+ve organisms.
Precaution
Pregnancy and lactation. Avoid contact with eyes. Discontinue if irritation or sensitisation occurs. Cross-sensitisation with other imidazole derivatives may occur. Lactation: distributed into milk; use with caution in nursing women

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Side Effect
1-10% Pruritus (1-2%),Burning (1-2%) <1% Irritation,Stinging,Erythema,Rash,Folliculitis,Papules,Nodules,Maceration,Fissuring _