Medicine Overview of Siloflo 4mg Capsule
Introduction
Siloflo 4 is an alpha adrenergic antagonist that is used in the treatment of benign prostatic hyperplasia. It helps to relieve symptoms like difficulty in passing urine. However, it does not decrease the size of the prostate. Siloflo 4 is advised to take it in a dose and duration as per prescription. It should be taken with food, but take at the same time regularly. Swallow the medicine as a whole without crushing or chewing it. You should not stop taking the medicine without consulting the doctor as it may lead to the worsening of your symptoms. The course of
Uses of Siloflo 4
- Benign prostatic hyperplasia
Side effects of Siloflo 4
Common
- Retrograde ejaculation
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Dizziness
- Headache
- Nasal congestion (stuffy nose)
- Diarrhea
How to use Siloflo 4
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Siloflo 4 is to be taken with food.
How Siloflo 4 works
Siloflo 4 is an alpha blocker. It works by relaxing muscle around the bladder exit and prostate gland so urine is passed more easily.
What if you forget to take Siloflo 4?
If you miss a dose of Siloflo 4, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
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Siloflo 4 helps in relieving the symptoms of enlarged prostate. It does not decrease the size of the prostate.
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Siloflo 4 must be taken with food.
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You will feel better within hours or days of starting the treatment. Full effect is usually seen within 2 weeks.
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Siloflo 4 may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
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If you are scheduled to undergo an eye surgery due to cataract or glaucoma, inform your eye doctor about the usage of Siloflo 4.
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Inform your doctor if you have ever been diagnosed with kidney or liver problems.
Brief Description
Indication
Treating the signs and symptoms of enlarged prostate (benign prostatic hyperplasia [BPH]).
Adult Dose
Benign Prostatic Hyperplasia
Adults
PO 8 mg once daily with a meal.
Adults
PO 8 mg once daily with a meal.
Hepatic Impairment
Mild-to-moderate impairment (Child-Pugh class A or B): Dose adjustment not necessary
Severe Impairment: (Child-Pugh class C): Contraindicated (not studied)
Renal Dose
Renal Impairment
CrCl <50 mL/min: Dose adjustment not necessary
CrCl 30-50 mL/min: 4 mg PO qDay
CrCl <30 mL/min: Contraindicated
CrCl <50 mL/min: Dose adjustment not necessary
CrCl 30-50 mL/min: 4 mg PO qDay
CrCl <30 mL/min: Contraindicated
Contraindication
Hypersensitivity.
Mode of Action
Selectively blocks postsynaptic alpha-1 adrenoreceptors located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra.
Precaution
Impaired hepatic & renal function. Start treatment w/ a low dose (2 mg/dose).
Side Effect
>10%
Retrograde ejaculation (28%)
Retrograde ejaculation (28%)
1-10%
Diarrhea (3%),Headache (2%),Insomnia ((1-2%),Dizziness (3%),Orthostatic hypotension (3%; increased in patients >65 years),Nasopharyngitis (2%),Nasal congestion (2%),Sinusitis (1-2%)
Interaction
Ketoconazole, digoxin.
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