Tazoskin

Introduction
Tazoskin is a medicine used in the treatment of psoriasis. It works by stopping the overgrowth and thickening of skin cells. Use it only on the affected areas and do not apply on the healthy skin. Tazoskin is for external use only. You should always use it exactly as your doctor has told you. The affected area should be clean and dry before application. You must wash your hands thoroughly before and after applying this medicine. This medicine should be used regularly to get the most benefit from it. Do not use more than you need as it will not clear your condition faster and some side effects may be increased. If your condition goes on for longer than four weeks or gets worse at any time, let your doctor know. You can help this medicine work better by keeping the affected areas clean. Common side effects include itching, skin redness, irritation, dry skin, skin burn, and skin peeling at the site of application. Most of these are temporary and usually resolve with time. Please consult your doctor if these side effects persist for a longer duration. Avoid direct contact of the cream or ointment with your eyes. In case of direct contact, wash your eyes with water and seek immediate medical attention. Avoid sun exposure and cover the treated areas with clothing or use a sunscreen before stepping out in the sun. Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding as it may lead to birth defects.

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Uses of Tazoskin
Psoriasis
Acne
Side effects of Tazoskin
Common
Dry skin
Erythema (skin redness)
Itching
Skin burn
Skin irritation
Skin peeling
How to use Tazoskin
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
How Tazoskin works
Tazoskin is a form of vitamin A. It works by slowing down the rapid growth of skin cells, and blocks certain substances which cause inflammation (redness and swelling) on skin. This reduces scaling and thickening of the skin in psoriasis and clears acne.
Quick Tips
Tazoskin should be applied as per dose and duration suggested by the doctor.
Finish the full course of treatment even if you feel better.
Wash your hands properly before and after applying the medicine.
Avoid getting in the eyes, nose, or mouth. If accidental exposure occurs, rinse immediately with plenty of water.
Avoid exposing your skin to strong sunlight, use a sunscreen lotion or make sure your skin is protected with clothing.
Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
Inform your doctor if the infection has not cleared up after four weeks of treatment.
Brief Description
Indication
Acne, Stable plaque psoriasis, Photo aging
Adult Dose
Topical/Cutaneous Acne, Stable plaque psoriasis Apply a thin layer to cleansed dry affected area, once daily in the evening. Photoaging Adult: Apply a thin layer to cover entire face (including eyelids) once daily before going to bed.

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Child Dose
<12 years: Safety and efficacy not established >12 years: Apply to affected area once daily in the evening.

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Contraindication
Pregnancy, lactation. Eczema. Sunburnt conditions. Hypersensitivity.
Mode of Action
Tazarotene is a synthetic acetylenic retinoid, that is applied topically. It is de-esterified in the skin to its active form, tazarotenic acid, which affects cell proliferation and differentiation by modulating gene expression in acne and psoriasis.
Precaution
Avoid contact with eyes, mouth, mucous membranes. Abraded skin. Avoid exposure to sun or UV light. Do not use >10% of BSA. Do not use cream with occlusive dressing. Wash hands after application. Do not use cream/gel in amounts more than instructed. Women of child bearing potential should take birth control measures. Negative pregnancy test to be obtained within 2 wk prior to initiation and start therapy during normal menstrual period. Retinoid should not be used on eczematous skin, as they may cause severe irritation. Because of heightened burning susceptibility, exposure to sunlight (including sunlamps) should be avoided unless deemed medically necessary and in such cases, exposure should be minimized during the use of Tazarotene cream. Tazarotene cream should be administered with caution if the patient is also taking drugs known to be photosensitizers (e.g., thiazides, tetracyclines, fluoroquinolones, phenothiazines, sulfonamides) because of the increased possibility of augmented photosensitivity.

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Side Effect
>10% Desquamation,Erythema,Burning/stinging,Dry skin 1-10% Skin irritation (1% -22%),Skin pain,Pruritis,Irritant or contact dermatitis,Stinging,Acne,Photosensitivity,Rash,Cheilitis Frequency Not Defined Worsening of psoriasis,Eczema,Rash,Dry skin,Skin inflammation,Fissuring,Bleeding,Peripheral edema,Hypertriglyceridemia

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Interaction
Increased drying effect effect with concomitant use of dermatologic medications and cosmetics that have irritant or strong drying effect. Increased risk of photosensitivity with drugs known to be photosensitisers.